other material
confidence high
sentiment positive
materiality 0.75
Phio Pharmaceuticals announces SMC recommendation to escalate to third dose cohort in PH-762 Phase 1b trial
Phio Pharmaceuticals Corp.
- Safety Monitoring Committee reviewed safety data from second dose cohort and recommended escalation to next dose concentration.
- First two patients in second cohort showed complete response (100% tumor clearance) and partial response (90% clearance) at Day 36.
- No dose-limiting toxicities or serious adverse events reported in participants receiving intratumoral PH-762.
- PH-762 is being studied for cutaneous squamous cell carcinoma, melanoma, and Merkel cell carcinoma in Phase 1b trial.