other material
confidence high
sentiment neutral
materiality 0.65
Lantheus to release SPLASH trial data in Oct 2024 after 75% OS events reached
Lantheus Holdings, Inc.
- Expects to release Phase 3 SPLASH data in October 2024 for 177Lu-PNT2002 in PSMA-expressing mCRPC.
- Release triggered by reaching 75% of protocol-specified target overall survival events.
- Trial randomized 412 patients 2:1; 84.6% of control arm crossed over to PNT2002.
- Primary endpoint is radiographic progression-free survival; 80% of patients from North America.