Equillium stockholders approve reverse stock split and authorized share increase at annual meeting

Proposal 1. Election of directors. The Company’s stockholders elected the two persons listed below as Class II directors, each to serve until the Company’s 2029 Annual Meeting of Stockholders and until their respective successor has been duly elected and qualified, or until their earlier death, resignation or removal. Former director Peter Colabuono was not renominated as a director and his term ended at the Annual Meeting. In connection with the expiration of Mr. Colabuono’s term, the Company reduced the size of the Board of Directors from seven directors to six directors. The final voting results are as follows: Name Votes For Votes Withheld Broker Non- Votes Charles McDermott 36,072,238 10,018,889 8,196,202 Bruce Steel 45,955,052 136,075 8,196,202

Proposal 4. Approval of an amendment to the Company’s Amended and Restated Certificate of Incorporation. The Company’s stockholders approved an amendment to the Company’s Amended and Restated Certificate of Incorporation to increase the authorized number of shares of common stock from 200,000,000 to 400,000,000 shares. The final voting results are as follows: Votes For Votes Against Abstentions Broker Non-Votes 42,687,545 11,570,307 29,477 0

Proposal 3. Ratification of the appointment of the independent registered public accounting firm. The Company’s stockholders ratified the appointment by the Audit Committee of the Company’s Board of Directors of Crowe LLP as the Company’s independent registered public accounting firm for the fiscal year ending December 31, 2026. The final voting results are as follows: Votes For Votes Against Abstentions Broker Non-Votes 54,274,675 5,234 7,420 0

Proposal 2. Approval of an amendment to the Company’s Amended and Restated Certificate of Incorporation to effect a reverse stock split. The Company’s stockholders approved an amendment to the Company’s Amended and Restated Certificate of Incorporation to effect a reverse stock split of the Company’s common stock at a ratio in the range of 1-for-2 to 1-for-20, inclusive, with such ratio to be determined in the discretion of the Company’s Board of Directors and with such reverse stock split to be effected at such time and date, if at all, as determined by the Company’s Board of Directors in its sole discretion. The final voting results are as follows: Votes For Votes Against Abstentions Broker Non-Votes 52,697,618 1,559,976 29,735 0