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Equillium stockholders approve reverse stock split and authorized share increase at annual meeting
Reverse stock split approved at ratio of 1-for-2 to 1-for-20, with timing and ratio at Board's discretion.
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Equillium Q1 net loss narrows to $5.3M; EQ504 Phase 1 on track for mid-2026
Q1 net loss of $5.3M ($0.06/sh) vs. $8.7M ($0.24/sh) in Q1 2025; R&D spending down to $3.0M.
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Equillium Q4 2025 revenue $0, net loss $3.8M; cash runway into 2029 after $35M financing
Q4 2025 revenue $0 (vs $4.4M Q4 2024); FY2025 revenue $0 (vs $41.1M FY2024 from Ono deal).
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Equillium raises ~$35M in private placement with RA Capital to fund EQ504
Issued 1,179,508 shares at $1.854/share and pre-funded warrant for up to 17,698,593 shares at $0.0001 exercise price.
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Equillium reports Q3 net loss of $4.2M; announces $50M financing and EQ504 Phase 1 plan for mid-2026
Q3 2025 revenue $0 vs $12.2M in prior year; net loss $4.2M ($0.06 per share) vs $7,000 loss in Q3 2024.
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Equillium confirms Crowe LLP as auditor for FY2025, effective Oct 21, 2025
Engagement letter with Crowe LLP executed Oct 21, 2025; client acceptance procedures completed same day.
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Equillium ends Biocon itolizumab deal, dismisses KPMG, two directors resign
Terminated collaboration with Biocon; all itolizumab licenses reverted. Technical service fee of $363k set-off against amounts owed.
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Equillium ups ATM facility to $75M from $21.95M; prior sales $0.96M
Filed prospectus supplement to increase aggregate offering price of common stock under existing Sales Agreement to $75M.
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Equillium regains Nasdaq minimum bid price compliance
Nasdaq notified Equillium on Aug 29, 2025 that it has regained compliance with the $1.00 minimum bid price rule.
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Equillium raises $30M in private placement; cash runway through 2027
Initial closing of 21.8M shares at $0.57/sh and pre-funded warrants for 30.8M shares, gross proceeds $30M.
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Equillium adopts crypto treasury strategy; cash $11.5M, runway into Q4 2025; going concern doubt
Cash and cash equivalents $11.5M as of June 30, 2025; expects to fund operations into Q4 2025.
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Equillium receives Nasdaq extension to Dec 8, 2025 for bid price compliance
Nasdaq granted Equillium (EQ) until Dec 8, 2025 to regain minimum $1.00 bid price compliance.
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Equillium stockholders approve reverse stock split and equity plan amendment
Stockholders authorized reverse stock split at ratio 1:2 to 1:20, with board discretion on timing and ratio.
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Equillium announces FDA declined Breakthrough Therapy and Accelerated Approval for itolizumab in aGVHD
FDA declined Breakthrough Therapy designation and Accelerated Approval for itolizumab in aGVHD based on EQUATOR study data.
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Equillium Reports Q4 and Full Year 2024 Financial Results and Provides Clinical Updates
Phase 3 EQUATOR study in aGVHD: primary endpoint not met, but statistically significant longer-term outcomes (CR at Day 99, duration of CR, failure-free survival).
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Equillium reports itolizumab Phase 2 UC topline: 23.3% clinical remission vs 10% placebo
Primary endpoint: 23.3% clinical remission at week 12 for itolizumab vs 20.0% adalimumab, 10.0% placebo.
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Equillium receives Nasdaq minimum bid price non-compliance notice; cure period until June 11, 2025
Nasdaq notified Equillium on Dec 13, 2024 that common stock bid price was below $1.00 for 30 consecutive business days.
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Equillium director Yu Xu resigns; Peter Colabuono appointed to board
Yu (Katherine) Xu, Ph.D., resigned from Equillium board and audit committee effective Dec 10, 2024; no disagreement cited.
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Equillium Q3 revenue $12.2M, net loss near zero; retains itolizumab rights after Ono termination
Q3 revenue $12.2M (up 37% YoY) from Ono partnership; net loss ~$7,000 vs $3.7M loss in Q3 2023.
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Equillium regains Nasdaq minimum bid price compliance after meeting $1.00 close for 10 days
Received Nasdaq notice on Oct 30, 2024 confirming compliance regained as of Oct 29, 2024.
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Equillium announces Ono option lapse; pauses EQUATOR enrollment to review acceleration; cash runway into Q4 2025
Ono's option to acquire itolizumab (EQ001) lapsed; Equillium retains all commercial rights to itolizumab.
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Equillium Q2 net income $0.5M, revenue $13.9M; Ono itolizumab option decision by Oct 2024
Net income $0.5M ($0.01 EPS) vs net loss $3.3M in Q2 2023; revenue $13.9M (all from Ono collaboration), up from $9.1M.
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Equillium receives Nasdaq bid price deficiency notice; cure deadline Jan 15, 2025
Received Nasdaq notice on July 19, 2024 for bid price below $1.00 for 30 consecutive business days.
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Equillium estimates cash balance of $33.3M as of June 30, 2024
Preliminary cash, cash equivalents and short-term investments approximately $33.3 million as of June 30, 2024.
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Equillium reports Phase 2 topline data for EQ101 in alopecia areata; 20% of completers achieved SALT ≤20
Of 25 completers (baseline SALT 35-100), 20% reached SALT ≤20 at week 24; mean SALT improvement 13.5%.
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Equillium stockholders approve reverse stock split amendment at annual meeting
Approved amendment to certificate of incorporation for reverse stock split at ratio of 1:2 to 1:10, with board discretion on timing and ratio.
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Equillium Q1 revenue $10.7M, net loss $2.7M; positive lupus data, milestones ahead
Revenue of $10.7M, up from $8.9M YoY, all from Ono partnership (development funding and amortization).
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Equillium reports positive Phase 1b itolizumab data in lupus nephritis
Topline data: 16 patients; baseline mean UPCR 4.9 g/g → ~73% reduction; overall response rate 81.3% (CR+PR).
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Equillium reports $40.9M cash; EQ101 Phase 2 topline due Q2; Ono itolizumab option decision 2H 2024
Cash $40.9M at Dec 31, 2023; runway into 2H 2025.
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Equillium appoints Penny Tom as principal accounting officer; adopts 2024 Inducement Plan
Penny Tom, SVP Finance, appointed principal accounting officer effective March 6, 2024; Jason Keyes remains CFO.
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Equillium reports $40.9M cash prelim as of Dec 31, 2023; upsizes ATM to $21.95M
Preliminary cash, equivalents & short-term investments of $40.9M as of Dec 31, 2023 (unaudited).
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Equillium regains Nasdaq compliance with $1.00 minimum bid price rule
Received Nasdaq letter on Feb 21, 2024 confirming compliance with Bid Price Rule.
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Equillium completes EQ101 Phase 2 enrollment for alopecia areata; advances EQ302 over EQ102
Completed enrollment of 36 patients in EQ101 Phase 2 study for alopecia areata; topline data expected Q2 2024.
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Equillium Q3 net loss narrows to $3.7M; lupus trial meets endpoints
Net loss $3.7M ($0.11 per share) vs $13.7M loss in Q3 2022, driven by $8.9M revenue from Ono partnership.
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Equillium presents pre-clinical data for oral EQ302 targeting IL-15/IL-21; analysts day held
EQ302 is an orally deliverable multi-cytokine inhibitor targeting IL-15 and IL-21.
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Equillium enters new ATM equity facility with Jefferies; gets Nasdaq extension to April 2024
New ATM offering agreement with Jefferies; 3.0% commission on gross proceeds; no maximum offering amount disclosed.
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Equillium Q2 2023 net loss narrows to $3.3M; cash $48.4M; stock repurchase authorized
Revenue of $9.1M from Ono partnership; net loss $0.10/sh vs $0.41/sh loss year ago.
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Equillium repays $6.8M loan from Oxford Finance and Silicon Valley Bank, terminates agreement
Prepaid all amounts under Loan and Security Agreement dated September 30, 2019 with Oxford Finance LLC and Silicon Valley Bank.
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Equillium stockholders approve reverse stock split authorization at 2023 annual meeting
Reverse stock split authorized at ratio of 1-for-2 to 1-for-10; board to set final ratio and timing.
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Equillium Q1 net loss narrows to $3.9M; cash $62M funds into 2025; Ono partnership revenue $8.9M
Net loss of $3.9M ($0.11 per share) vs $37.4M loss in Q1 2022; decrease due to Ono revenue and no Bioniz acquisition costs.
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Equillium receives Nasdaq bid price deficiency notice; has until Oct 2, 2023 to regain compliance
Nasdaq notified Equillium on April 5, 2023 that its common stock bid price closed below $1.00 for 30 consecutive business days.
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Equillium Q4 2022: $15.8M revenue from Ono deal, net income $2.8M; cash $71M into 2025
Revenue of $15.8M in Q4 2022 from Ono Pharmaceutical asset purchase agreement; no revenue in prior year period.
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Equillium and Metacrine mutually terminate merger; no fee; cash runway extended via Ono partnership
Merger agreement terminated effective Dec 23, 2022; no termination fee payable.
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Equillium amends merger disclosures following three Metacrine stockholder lawsuits
Three lawsuits filed by Metacrine stockholders challenge disclosures in joint proxy for merger with Equillium.
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Equillium receives $26M upfront from Ono for itolizumab option; up to $138.5M in milestones
Upfront payment of $26.0M (¥3.5B) non-refundable; option exercise payment of $37.1M (¥5.0B) if exercised.
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Equillium Q3 net loss $13.7M ($0.40/shr); Metacrine deal to add $35M cash
Net loss $13.7M ($0.40/shr) vs $10.3M ($0.35) in Q3 2021; R&D $8.8M, G&A $4.5M.
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Equillium reports interim itolizumab data in LN: 50% CR at week 28, 67% >80% UPCR reduction
Baseline mean UPCR 5.8 g/g; 13 subjects enrolled, 11 reached week 12, 6 reached week 28/EOS.
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Equillium files Metacrine financials and pro forma statements for pending merger
Metacrine 2021 net loss $62.2M; accumulated deficit $182.95M as of Dec 31, 2021.
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Equillium to acquire Metacrine in all-stock deal; adds $33M cash, MET642 candidate
All-stock merger adds ~$33M cash to Equillium's balance sheet, extending runway into 2024.
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Equillium Q2 net loss $14.1M (-$0.41/sh); cash $57.6M; clinical pipeline on track
Net loss $14.1M, or $(0.41) per share, vs $9.2M ($0.31) in Q2 2021; R&D spend $9.5M.