other material
confidence medium
sentiment neutral
materiality 0.40
Calidi presents RTNova data supporting systemic targeting of metastatic lung cancer at IOVC and SITC
Calidi Biotherapeutics, Inc.
- Data presented at IOVC and SITC shows RTNova enveloped virotherapy can target multiple metastatic tumor sites.
- RTNova uses tumor-selective vaccinia virus engineered to produce high levels of EEVs to avoid immune clearance.
- In an advanced lung metastasis model, RTNova demonstrated robust therapeutic potential as monotherapy and viral vector.
- The platform can induce expression of engineered payloads in tumor cells, enabling future delivery of therapeutic genes.
- Calidi plans to advance RTNova as a multi-modal systemic antitumor virotherapy and seek pharma collaborations.