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Corbus reports CRB-701 42.9% cORR in 2L OPSCC at 3.6 mg/kg; registrational study planned summer 2026
cORR 42.9% (9/21) in 2L OPSCC at 3.6 mg/kg; median DOR 6.3 mo, PFS 5.6 mo.
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Corbus appoints Nishant Saxena as first Chief Business Officer; schedules CRB-701 data call
Nishant Saxena appointed CBO; base salary $470K, 192,300 options and 58,300 RSUs as initial equity.
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Corbus appoints Brent Pfeiffenberger to board; shareholders approve 3M share increase for equity plan
Appointed Brent Pfeiffenberger (CEO Century Therapeutics, former SVP BMS) to board, expanding to 7 members.
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Corbus Q1 net loss $23M, cash $138.2M; FDA alignment for CRB-701 registration path
Net loss of $23.0M ($1.23 diluted LPS) vs $17.0M loss ($1.39 LPS) in Q1 2025.
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Corbus Pharma amends employment agreements: CEO salary $673,625, CFO salary $501,273
New employment agreements for CEO Yuval Cohen and CFO Sean Moran, effective April 15, 2026.
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Corbus completes enrollment in CANYON-1 Phase 1b trial of CRB-913 for obesity; on track for summer 2026 data
Last patient enrolled and completed first visit in CANYON-1 Phase 1b trial of CRB-913, a peripherally restricted oral CB1 inverse agonist.
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Corbus Pharma announces FDA alignment for CRB-701 accelerated path; CMO resigns
FDA agreed on registrational study designs for CRB-701 in second-line HNSCC and cervical cancer, with potential accelerated approval using ORR primary endpoint.
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Corbus Q4 net loss $20.6M; cash $163.3M into 2028; key CRB-701/913 catalysts mid-2026
Q4 2025 net loss $20.6M ($1.25/share) vs $9.5M ($0.78) in Q4 2024; operating expenses rose to $22.0M.
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Corbus Pharmaceuticals updates investor presentation; no specifics extractable from truncated exhibit
Corbus Pharmaceuticals Holdings updated its corporate investor presentation on February 25, 2026.
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Corbus updates investor presentation; no new material financial or operational data disclosed
Furnished updated corporate presentation under Item 7.01 Regulation FD.
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Director Alan Holmer resigns from Corbus board effective Dec 31, 2025
Alan Holmer notified Corbus of his resignation from the Board on Dec 12, 2025, effective Dec 31, 2025, citing retirement.
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Corbus posts Phase 1a data for CRB-913: weight loss signal, no serious AEs; Phase 1b started
Phase 1a SAD/MAD of oral CB1 inverse agonist CRB-913 (n=112) showed no serious AEs, no GI intolerability, no neuropsychiatric events except mild anxiety/irritability in obese cohort.
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Corbus Q3 net loss $23.3M ($1.90/sh); cash $104M; CRB-701 ORR 47.6% in HNSCC
Net loss of $23.3M ($1.90 diluted EPS) vs $13.8M ($1.15) in Q3 2024; operating expenses up $8.9M.
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Corbus Pharmaceuticals prices $75M public offering of common stock and warrants
Offering of 4,744,231 shares at $13.00/share and 1,025,000 pre-funded warrants at $12.9999 each for ~$75M gross proceeds.
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Corbus reports preliminary Q3 cash position of $104M as of Sep 30, 2025
Expected cash, cash equivalents, and investments of approximately $104.0 million.
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Corbus Pharma reports CRB-701 Phase 1/2 ORR 47.6% HNSCC, 55.6% mUC at ESMO25
3.6 mg/kg dose: ORR 47.6% in HNSCC (n=21), 37.5% in cervical cancer (n=16), 55.6% in mUC (n=9).
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FDA grants Fast Track designation for Corbus' CRB-701 in recurrent/metastatic HNSCC
FDA granted Fast Track for CRB-701 to treat HNSCC after prior platinum and anti-PD(L)-1 therapy.
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Corbus Pharmaceuticals Q2 2025 Net Loss $17.7M, Pipeline on Track for Data Readouts H2 2025
Net loss for Q2 2025 was $17.7 million ($1.44 per share), compared to $10.0 million loss in Q2 2024.
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Corbus Pharma shareholders elect directors, ratify auditor, approve say-on-pay; Rachelle Jacques appointed Board Chair
All seven director nominees elected (Yuval Cohen, Alan Holmer, Rachelle Jacques, John Jenkins, Anne Altmeyer, Yong Ben, Winston Kung; broker non-votes 2,281,655).
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Corbus Pharma Q1 net loss $17M; pipeline on track for data in H2 2025
Net loss of $17.0M ($1.39/share) vs $6.9M ($0.83) in Q1 2024; operating expenses rose to $19.8M.
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Director Peter Salzmann not standing for re-election; board size reduced to seven
Dr. Salzmann will not stand for re-election at the 2025 annual meeting.
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Corbus appoints Ian Hodgson as COO effective March 15, 2025
Ian Hodgson, 52, previously Head of Operations, named COO effective March 15, 2025.
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Corbus reports Q4 net loss $9.5M, cash $149.1M; pipeline updates on CRB-701, CRB-913, CRB-601
Net loss Q4 2024 $9.5M ($0.78/share) vs $8.0M ($1.81/share) in Q4 2023; full-year loss $40.2M ($3.68/share).
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Corbus CRB-701 Phase 1 Western data: low neuropathy, HNSCC responses, dose optimization started
No DLTs; peripheral neuropathy 5% (Grade 1-2) vs 3% in China; combined 4% across 75 patients.
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FDA grants Fast Track designation to Corbus' CRB-701 for cervical cancer
CRB-701 is a next-generation Nectin-4 ADC with site-specific cleavable linker, MMAE payload, DAR 2.
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Board member Anne Altmeyer adopts 10b5-1 plan to sell up to 2,452 shares of CRBP common stock
Anne Altmeyer, Ph.D., board member, adopted Rule 10b5-1 plan on Nov 14, 2024.
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Corbus Q3 net loss $13.8M; CRB-701 dose escalation complete; cash $159.4M
Net loss of $13.8M ($1.15/diluted share) vs $10.1M ($2.27) in Q3 2023; operating expenses up $6.0M to $15.5M.
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Corbus presents pre-clinical data for obesity drug CRB-913; Phase 1 start Q1 2025
CRB-913 showed 15-fold lower brain levels vs monlunabant in mice; plasma-to-brain ratio 10x better than monlunabant.
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Director John Jenkins adopts 10b5-1 plan to sell up to 5,436 CRBP shares
Plan covers up to 5,436 shares of common stock, effective November 30, 2024.
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Corbus Pharmaceuticals appoints Winston Kung to Board, replaces exiting director Chip Catlin
Avery 'Chip' Catlin resigned from Board and as Audit Chair effective Aug 15, 2024; no disagreement with company.
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Corbus Pharma Q2 loss $10M; CRB-701 shows 44% ORR in mUC; cash runway through Q3 2027
Net loss of $10.0M ($0.90 per diluted share) for Q2 2024, compared to net loss of $8.8M ($2.05 per share) in Q2 2023.
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Corbus files updated corporate presentation; no substantive news identified
Corbus Pharmaceuticals furnished an updated corporate investor presentation on August 6, 2024.
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Corbus board member Dr. Yong Ben adopts 10b5-1 plan for up to 10,607 shares
Dr. Yong Ben, a board member, adopted a Rule 10b5-1 trading plan on June 14, 2024.
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Corbus reports Phase 1 data for CRB-701 at ASCO: 44% ORR in mUC, 43% in cervical cancer
44% ORR and 78% DCR in mUC (n=9), 43% ORR and 86% DCR in cervical cancer (n=7) at doses ≥1.2 mg/Kg.
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Corbus stockholders approve 2024 Equity Compensation Plan reserving 2M shares
Stockholders approved 2024 Equity Compensation Plan, reserving 2,000,000 shares of common stock for issuance under options, SARs, restricted stock, RSUs, and performance awards.
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Corbus updates risk factors; no new operational or financial events
Filing supplements risk factors for Q1 2024; no change in business outlook.
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Corbus Q1 net loss narrows to $6.9M; raised $116M, cash runway through Q1 2027
Net loss of $6.9M ($0.83/diluted share) vs $17.7M ($4.24) in Q1 2023, driven by lower operating expenses.
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Corbus enters amended employment agreements with CEO and CFO; base salaries $622,804 and $463,455
CEO Yuval Cohen's 2-year agreement: base salary $622,804, bonus target up to 60% of base.
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CEO and CFO adopt Rule 10b5-1 trading plans for up to 159,672 shares
CEO Yuval Cohen plan: sale of up to 117,066 shares beginning June 13, 2024, ending March 15, 2025.
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Corbus Pharma reports Q4 net loss $8.0M; cash $127M after $116M raise; CRB-701 shows 43% ORR
Net loss Q4 $8.0M ($1.81/diluted) vs $10.9M ($2.61) YoY; full year loss $44.6M ($10.31).
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Corbus Pharmaceuticals CSO Rachael Brake resigns effective Feb 19, 2024
Chief Scientific Officer Rachael Brake submitted resignation on Feb 2, 2024.
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Corbus Pharmaceuticals updates investor presentation; no material changes disclosed
Filed updated corporate presentation dated February 2, 2024, as Exhibit 99.1.
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Corbus Pharmaceuticals files non-substantive 8-K/A to correct Exhibit 5.1 signature
Amendment corrects omitted conformed signature on Lowenstein Sandler LLP legal opinion filed as Exhibit 5.1.
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Corbus Pharmaceuticals prices public offering of 4.325M shares at $19, expects ~$88.5M net proceeds
Priced 4,325,000 shares of common stock at $19.00 per share; underwriters' option for additional 648,750 shares exercised in full.
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Corbus suspends ATM equity offering program, terminates Jan 29 prospectus supplement
Suspended and terminated the ATM prospectus supplement dated Jan 29, 2024, under Sale Agreement with Jefferies.
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Corbus reports preliminary cash of $20.9M as of Dec 31, 2023; raised $16.8M via ATM
Raised approximately $16.8M in gross proceeds from common stock sales under Open Market Sale Agreement with Jefferies.
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Corbus announces Phase 1 data for CRB-701: 43% ORR at therapeutic doses, no peripheral neuropathy or skin rash
Phase 1 dose-escalation data for CRB-701 (SYS6002) in nectin-4 positive tumors presented at ASCO GU 2024.
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Corbus receives FDA IND clearance for CRB-601; Nasdaq grants extension to May 8, 2024
FDA cleared IND for CRB-601, a TGFβ blocking monoclonal antibody targeting integrin αvβ8.
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Corbus files routine investor presentation update; no material new information
Filing includes an updated corporate slide deck dated November 2023.
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Corbus receives Nasdaq delisting notice for equity below $2.5M minimum
Nasdaq notified Corbus on Nov 10, 2023 that stockholders' equity of $311,016 as of Sept 30, 2023 is below the $2.5M minimum for continued listing.