Dr. Reginald Sanders
appointed Dr. Reginald Sanders, M.D. to fill the vacancy on the Board, effective January 8, 2025.
Highest-materiality recent filing
EyePoint Q2 net loss $94.5M ($1.09/sh); cash $180M; LUGANO data expected August 2026
Net loss $94.5M vs $59.4M YoY; revenue $0.5M vs $5.3M.
EyePoint completes enrollment in both Phase 3 DME trials of DURAVYU; topline data Q4 2027
Over 480 patients enrolled across COMO and CAPRI trials in five months, ahead of schedule.
EyePoint settles DOJ False Claims Act probe for $4.68M; enters 5-year CIA
Settlement payment of $4,678,981.86 plus 4.25% interest from Jan 28, 2026, due within 14 days.
EyePoint receives third positive DSMC recommendation for Phase 3 wet AMD DURAVYU trials
DSMC recommends LUGANO and LUCIA continue without modification; all active treatment-arm patients have received second DURAVYU dose.
EyePoint Q1 net loss $84.8M ($0.99/share); DURAVYU Phase 3 wet AMD data expected mid-2026
Q1 2026 revenue $0.7M vs $24.5M YoY, driven by YUTIQ license deferral; operating expenses $87.9M.
EyePoint files defamation lawsuit against Ocular Therapeutix over false statements about DURAVYU
Complaint filed March 20, 2026 in Middlesex County Superior Court (Massachusetts).
EyePoint Q4 net loss $67.6M; DURAVYU wet AMD Phase 3 topline due mid-2026
Net loss Q4 $67.6M ($0.81/sh) vs $41.4M ($0.64); FY net loss $232M ($3.17) vs $130.9M ($2.32).
EyePoint doses first patients in Phase 3 DME trials for DURAVYU; topline data 2H 2027
First patients dosed in global Phase 3 COMO and CAPRI trials of DURAVYU (vorolanib intravitreal insert) for diabetic macular edema.
EyePoint provides 2026 clinical milestones; ~$300M cash; wet AMD data mid-2026
Phase 3 LUGANO (432 pts) wet AMD top-line data expected mid-2026; LUCIA (475 pts) data to follow.
EyePoint DSMC gives positive recommendation for Phase 3 DURAVYU wet AMD trials; no protocol changes
DSMC completed second scheduled review of Phase 3 LUGANO and LUCIA trials; no modifications recommended.
EyePoint Q3 net revenue $1.0M, net loss $59.7M; DURAVYU Phase 3 fully enrolled; $172.5M financing
Q3 2025 total net revenue fell to $1.0M from $10.5M YoY; net loss widened to $59.7M ($0.85/share) vs $29.4M ($0.54/share).
EyePoint raises ~$150M in public offering to fund DURAVYU clinical development
Pricing: 11M shares at $12.00 each; 1.5M pre-funded warrants at $11.999 each.
EyePoint initiates Phase 3 DURAVYU DME program; first patient Q1 2026; dual MOA data
First patient dosing in pivotal Phase 3 DME trials (COMO and CAPRI) expected Q1 2026; trials enroll ~240 patients each.
EyePoint Q2 net loss $59.4M; completes Phase 3 enrollment for DURAVYU in wet AMD
Net revenue $5.3M, down from $9.5M YoY; net loss $59.4M ($0.85/share) vs. $30.8M ($0.58/share) in Q2 2024.
EyePoint completes enrollment in both Phase 3 wet AMD trials for DURAVYU; topline data mid-2026
LUCIA enrolled over 400 patients in 7 months; combined LUGANO and LUCIA total over 800 patients.
EyePoint finishes Phase 3 enrollment for DURAVYU in wet AMD; top-line data mid-2026
LUCIA trial enrolled and randomized over 400 patients in seven months; total >800 across both trials.
EyePoint completes Phase 3 LUGANO enrollment for DURAVYU wet AMD; topline data mid-2026
Over 400 patients enrolled/randomized in seven months, one of fastest Phase 3 wet AMD trials.
EyePoint Q1 net loss $45.2M; DURAVYU Phase 3 wet AMD enrollment over 90% in LUGANO, >50% in LUCIA
Total net revenue $24.5M (up from $11.7M YoY); net loss $45.2M ($0.65 per share) vs $29.3M ($0.55) prior year.
EyePoint reports Q4 net loss $41.4M; DURAVYU Phase 3 enrollment ahead of expectations
Q4 net loss $41.4M ($0.64/share) vs $14.1M loss prior year; revenue $11.6M down from $14.0M.
EyePoint DURAVYU Phase 2 VERONA meets primary endpoint in DME; 2.7mg shows +7.1 letter BCVA gain
DURAVYU 2.7mg met primary endpoint with extended time to first supplemental injection vs aflibercept.
Phase 3 LUGANO trial for DURAVYU in wet AMD one-third enrolled; LUCIA trial tracking ahead of schedule; full enrollment target 2H 2025.
EyePoint dosed first patient in second Phase 3 wet AMD trial (LUCIA); topline data expected 2026
First patient dosed in LUCIA, the second global Phase 3 trial of DURAVYU (vorolanib Durasert E) for wet AMD.
EyePoint Q3 net loss $29.4M; positive DURAVYU interim data, $161M equity financing
Q3 net loss $29.4M ($0.54 per share) vs. $12.6M loss a year ago; revenue $10.5M down from $15.2M.
EyePoint closes upsized $161M public offering; net proceeds ~$151.1M for DURAVYU development
Closed offering of 14,636,363 shares at $11.00/share, including full underwriter option exercise for 1,909,090 additional shares.
EyePoint reports positive Phase 2 VERONA interim data for DURAVYU in DME; +8.9 letters BCVA
DURAVYU 2.7mg showed +8.9 letter improvement in BCVA vs +3.2 for aflibercept control at 16 weeks.
First patient dosed in global Phase 3 LUGANO trial of DURAVYU (vorolanib) for wet AMD; non-inferiority design vs aflibercept.
EyePoint Pharma appoints Fred Hassan to board; directors Guyer, Adamis resign for Merck roles
David Guyer and Anthony Adamis resigned from board effective Sept 3, 2024 due to full-time roles at Merck & Co.
EyePoint reports Q2 net loss of $30.8M; cash runway through DURAVYU Phase 3 topline in 2026
Net loss $30.8M ($0.58/sh) vs $22.9M loss ($0.61/sh) in Q2 2023; total net revenue $9.5M.
EyePoint announces Phase 3 plans for DURAVYU in wet AMD; positive Phase 2 data
Phase 3 LUGANO and LUCIA trials to enroll ~400 patients each; 2.7mg DURAVYU vs aflibercept; one-year endpoint.
EyePoint Q1 net loss $29.3M; DURAVYU Phase 2 NPDR trial misses primary endpoint; cash runway to 2026
Q1 net loss $29.3M ($0.55/shr) vs $21.2M ($0.56/shr) in Q1 2023; revenue $11.7M (+52% YoY) from YUTIQ deferred revenue.
EyePoint's DURAVYU misses Phase 2 NPDR primary endpoint; shows reduced progression at 9 months
Primary endpoint not met: 5% (3mg), 0% (2mg) vs 5% control achieved ≥2-step DRSS improvement at 9 months.
EyePoint reports Q4/FY2023 results; positive Phase 2 data for EYP-1901 in wet AMD
Q4 net loss $14.1M ($0.33/sh) vs $43.5M ($1.16/sh) YoY; total net revenue $14.0M (+33%).
EyePoint names Ramiro Ribeiro as Chief Medical Officer, replaces Dario Paggiarino
Ramiro Ribeiro appointed CMO effective March 1, 2024; succeeds Dario Paggiarino who leaves March 31.
EyePoint prices $200M public offering at $17/share to fund Phase 3 trials for EYP-1901
Underwritten public offering of 11,764,706 shares priced at $17.00 per share; underwriters exercised option for additional 1,764,705 shares.
EyePoint closes upsized $230M public offering for wet AMD Phase 3 trials
Closed upsized public offering of 13,529,411 shares at $17.00/share, raising ~$230M gross.
EyePoint reports positive Phase 2 DAVIO 2 topline for EYP-1901 in wet AMD; all endpoints met
Both EYP-1901 doses (2mg and 3mg) achieved non-inferiority in BCVA vs aflibercept (difference of -0.3 and -0.4 letters).
EyePoint Q3 net loss narrows to $12.6M; revenue up 52% on YUTIQ royalty recognition
Total net revenue $15.2M (up 52% YoY) driven by $14.4M in royalties from YUTIQ sale.
appointed Dr. Reginald Sanders, M.D. to fill the vacancy on the Board, effective January 8, 2025.
the Board, upon the recommendation of the Governance and Nominating Committee of the Board (the "Governance and Nominating Committee"), reduced the size of the Board from nine to eight members and appointed Fred Hassan to fill the remaining vacancy on the Board.
On September 3, 2024, David R. Guyer, M.D. and Anthony P. Adamis, M.D. resigned from the Board of Directors (the "Board") of EyePoint Pharmaceuticals, Inc. (the "Company") and all committees thereof, effective immediately.
On September 3, 2024, David R. Guyer, M.D. and Anthony P. Adamis, M.D. resigned from the Board of Directors (the "Board") of EyePoint Pharmaceuticals, Inc. (the "Company") and all committees thereof, effective immediately.
increased the size of the Board to ten (10) members and appointed Stuart Duty to fill the vacancy on the Board, effective October 16, 2023.
the Company appointed Dr. Duker as the Company's President and Chief Executive Officer, effective as of July 10, 2023
appointed Dr. Duker to fill the vacancy for the newly created directorship
Nancy S. Lurker transitioned from her role as Chief Executive Officer of EyePoint Pharmaceuticals, Inc. (the “Company”) to Executive Vice Chair of the Company.
Effective January 3, 2023 (the “Duker Start Date”), the Board of Directors (the “Board”) of the Company appointed Jay S. Duker, M.D., age 64, as the Company's President and Chief Operating Officer.
increased the size of the Board to eight members and appointed Karen Zaderej to fill the vacancy on the Board, effective immediately.
On January 10, 2022 (the “ Start Date ”), EyePoint Pharmaceuticals, Inc. (the “ Company ”) announced that the Board of Directors (the “ Board ”) of the Company appointed Michael C. Pine, age 46, as the Company’s Chief Corporate Development and Strategy Officer.
On November 1, 2021 (the “ COO Start Date ”), EyePoint Pharmaceuticals , Inc. (the “ Company ”) announced that the Board of Directors (the “ Board ”) of the Company appointed Jay S. Duker, M.D., age 63, as the Company's Chief Operating Officer.
Max materiality 0.85 · Median 0.70 · Most common event other_material