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Mirum Q2 net product sales $176M, raises FY guidance to $680-700M; volixibat NDA delayed to H1 2027
Q2 2026 net product sales $176.2M, up 38% YoY; LIVMARLI sales $128.7M (+46% YoY), Bile Acid Medicines $47.5M (+20% YoY).
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Mirum issues $690M zero-coupon convertible notes due 2032; exchanges $237M of 2029 notes
Issued $690M aggregate principal of 0.00% Convertible Senior Notes due 2032, including $90M option exercise.
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Mirum Q1 net sales $159.9M, raises FY guidance to $660-680M; volixibat & brelovitug meet primary endpoints
Q1 2026 net product sales $159.9M, up 43% YoY; LIVMARLI $113.8M (+55%), Bile Acid Medicines $46.1M (+20%).
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Mirum's volixibat meets primary endpoint in PSC Phase 2b VISTAS study with statistically significant itch reduction
Volixibat showed 2.72 point improvement in pruritus vs 1.08 for placebo; placebo-adjusted difference 1.64 (p<0.0001).
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Mirum's brelovitug meets Phase 2b primary endpoint in chronic HDV; 100% virologic response at 300 mg QW
100% of patients on 300 mg QW and 75% on 900 mg Q4W achieved virologic response vs 0% control.
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Mirum completes acquisition of Bluejay Therapeutics with $268.5M PIPE; Bluejay reports 2025 net loss of $101.7M
Concurrent PIPE raised $268.5M gross at $68.48/sh including pre-funded warrants.
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Mirum Pharma 2025 sales $521M (+55% YoY); guides 2026 $630-650M; multiple pipeline readouts in 2026
2025 net product sales $521.3M, up from $336.4M in 2024 (+55% YoY). LIVMARLI US sales $244.7M (+69% YoY).
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Mirum acquires Bluejay for $280.8M cash + stock; adds late-stage HDV therapy
Upfront consideration $280.8M cash plus ~4.67M shares; holdback $25.8M plus ~0.52M shares; up to $200M milestones.
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Mirum prelim 2025 sales ~$520M, above guidance; 2026 outlook $630-650M; acquiring Bluejay for HDV
Preliminary 2025 net product sales ~$520M, exceeding upper end of guidance.
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Mirum Pharmaceuticals secures additional $68.5M PIPE from TCGX ahead of Bluejay acquisition
1,000,000 shares at $68.48/share; ~$68.5M gross proceeds from TCGX.
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Mirum Pharmaceuticals sues Sandoz, Annora, Zydus, Zenara over generic Livmarli ANDAs
Received Paragraph IV notice letters from Sandoz, Annora Pharma, Zydus Lifesciences, and Zenara Pharma seeking generic Livmarli.
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Mirum Pharmaceuticals to Acquire Bluejay Therapeutics for Up to $820M
Mirum pays $250M cash and up to 5.2M shares (≈$370M) at closing, plus up to $200M in milestone payments for Bluejay Therapeutics.
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Mirum receives Sandoz Paragraph IV notice challenging Livmarli patents; plans to sue
Sandoz filed ANDA seeking FDA approval for generic Livmarli (maralixibat).
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Mirum Q3 revenue $133M, up 47% YoY; lifts FY guidance to $500-510M
Q3 2025 total revenue $133.0M vs $90.4M in Q3 2024; LIVMARLI sales $92.2M (+56% YoY).
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Mirum Q2 revenue $127.8M; raises FY 2025 guidance to $490-510M
Q2 global net product sales $127.8M, up 64% YoY from $77.9M.
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Mirum Q1 revenue $111.6M; raises 2025 guidance to $435-450M
Q1 2025 total revenue $111.6M vs $69.2M YoY, driven by LIVMARLI ($73.2M, +71%) and Bile Acid Medicines ($38.4M, +47%).
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Mirum reports 2024 net product sales $336.4M; guides 2025 sales $420M-$435M
2024 net product sales $336.4M, up from $178.9M in 2023; LIVMARLI sales $213.3M, Bile Acid Medicines $123.1M.
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Mirum Pharma 2024 net sales ~$336M, above guidance; 2025 outlook $420-435M
Preliminary unaudited FY2024 net product sales ~$336M, exceeding upper end of guidance range.
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Mirum Q3 net product sales $90.3M (+89% YoY); raises FY 2024 guidance to $330-335M
LIVMARLI net sales $59.1M; CHOLBAM/CHENODAL combined $31.2M.
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Mirum Q2 net product sales $77.8M (+139% YoY); LIVMARLI sales $47.2M; positive volixibat interim data
Q2 2024 global net product sales $77.8M, up 139% vs Q2 2023; full-year guidance reaffirmed at $310-320M.
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Mirum reports positive interim Ph2b data for volixibat in PBC and PSC
VANTAGE PBC trial: volixibat achieved placebo-adjusted -2.32 point itch reduction (p=0.0026); 75% of patients had >50% drop in serum bile acids.
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Mirum's LIVMARLI gets positive CHMP opinion for PFIC; EC decision in Q3 2024
CHMP adopted positive opinion for LIVMARLI (maralixibat) to treat PFIC in patients aged 3 months and older.
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Mirum Q1 revenue $69.2M, up 119% YoY; reaffirms FY guidance $310-320M
Global product sales net $68.9M, up 137% vs Q1 2023; LIVMARLI net sales $42.8M (+47%).
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Mirum reports 2023 net product sales of $178.9M (+142% YoY); guides 2024 sales $310-320M
Full-year 2023 total revenue $186.4M, up 142% over 2022; LIVMARLI net sales $141.8M (+89% YoY).
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Mirum announces preliminary 2023 net product sales of $178-180M; LIVMARLI sales up 89% YoY
Preliminary 2023 total revenue $186-188M; net product sales $178-180M.
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Mirum's LIVMARLI fails Phase 2b EMBARK trial in biliary atresia; primary endpoint not met
Phase 2b EMBARK trial of LIVMARLI (maralixibat) in biliary atresia did not meet primary or key secondary endpoints.
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Mirum acquires Bile Acid Business from Travere for up to $445M; H1 2023 revenue $53.6M, net income $13.6M
Acquired Chenodal and Cholbam assets for up to $445M ($210M upfront + up to $235M milestone payments).
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Mirum Q3 revenue $47.7M, LIVMARLI sales up 106%; CHENODAL/CHOLBAM acquisition completed
Q3 2023 total revenue $47.7M (up 154% YoY); LIVMARLI global net sales $38.7M, +106% vs Q3 2022.
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FDA extends review of Mirum's LIVMARLI sNDA for PFIC; new PDUFA date March 13, 2024
FDA extended PDUFA goal date to March 13, 2024, from original October 2023 target.
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Mirum appoints Eric Bjerkholt as CFO effective Sept 11, 2023
Eric Bjerkholt appointed CFO; previously CFO at Chinook Therapeutics and Aimmune Therapeutics.
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Mirum acquires Travere's bile acid products Cholbam and Chenodal for $210M upfront plus $235M milestones
Completed asset purchase of Cholbam and Chenodal from Travere for $210M cash at closing, with up to $235M in sales-based milestone payments.
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Mirum reports Q2 revenue $37.5M, LIVMARLI sales $32.5M; acquires CHENODAL/CHOLBAM for $210M
Q2 total revenue $37.5M (incl $5M license); LIVMARLI net sales $32.5M, up 86% YoY.
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Mirum to acquire Travere's bile acid portfolio for up to $445M; raises $210M PIPE to fund
Acquires Cholbam and Chenodal for $210M upfront plus up to $235M in sales-based milestones tiered from $125M to $500M in annual net sales.
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Mirum Q1 2023 LIVMARLI sales $29.1M, up 167% YoY; closed $316M convertible note
Net product sales for LIVMARLI $29.1M in Q1 2023 vs $10.9M in Q1 2022, a 167% increase.
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Mirum prices $316.25M 4.00% convertible notes due 2029; repurchases $192.7M revenue interests
Issued $316.25M principal (incl. full exercise of $41.25M over-allotment) of 4.00% convertible senior notes due May 1, 2029.
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Mirum reports $76M total rev in 2022; LIVMARLI net sales $74M; CFO Clements to step down
Total revenue $76M, LIVMARLI net product sales $74M for full year 2022 (preliminary unaudited).
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Mirum receives EC approval for LIVMARLI in Alagille syndrome across EU
European Commission granted marketing authorization for LIVMARLI (maralixibat) oral solution.
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Mirum discontinues OHANA Phase 2b trial of volixibat in ICP due to enrollment feasibility
Discontinued Phase 2b OHANA trial of volixibat for intrahepatic cholestasis of pregnancy (ICP).