Recent 8-K filings for TGTX
Highest-materiality recent filing
TG Therapeutics announces positive Phase 3 ENHANCE trial results for BRIUMVI consolidated dosing
- Phase 3 ENHANCE trial met primary endpoint, demonstrating bioequivalent drug exposure between single 600 mg Day 1 infusion and approved 150 mg Day 1 + 450 mg Day 15 regimen.
- Safety and tolerability of consolidated first infusion were consistent with established BRIUMVI profile; no Grade 3 or higher infusion reactions occurred.
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TG Therapeutics Q2 2026 revenue $240M, raises FY2026 BRIUMVI guidance to ~$890-905M
Q2 2026 total global revenue ~$240M; BRIUMVI U.S. net product revenue $227.7M, up 64% YoY.
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TG Therapeutics reports positive Phase 1 data for subcutaneous BRIUMVI; bioavailability >60% vs IV
Mean bioavailability >60% relative to IV; lower bound of 95% CI >55%.
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TG Therapeutics announces positive Phase 3 ENHANCE trial results for BRIUMVI consolidated dosing
Phase 3 ENHANCE trial met primary endpoint, demonstrating bioequivalent drug exposure between single 600 mg Day 1 infusion and approved 150 mg Day 1 + 450 mg Day 15 regimen.
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TG Therapeutics Q1 BRIUMVI US rev $194.8M; raises FY guidance to $885-900M
Q1 2026 total global revenue approx $205M; BRIUMVI U.S. net product revenue $194.8M (+63% YoY).
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TG Therapeutics establishes $750M term loan facility due 2031, repays prior term loans
Borrowed $750M on March 18, 2026 under new term loan; proceeds used to fully repay initial term loans.
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TG Therapeutics Q4 BRIUMVI US revenue $182.7M (+20% QoQ); 2026 revenue guidance raised to $875-900M
Q4 total revenue $192.6M; full year 2025 $616.3M; BRIUMVI US net revenue $594.1M (+92% YoY).
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TG Therapeutics prelim FY2025 global rev ~$616M; 2026 guided $875-900M
Preliminary FY2025 total global revenue ~$616M; U.S. BRIUMVI net product rev Q4 ~$182M, FY ~$594M.
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TG Therapeutics raises BRIUMVI revenue guidance to $585M, Q3 net income $390.9M
Q3 2025 total revenue $161.7M, BRIUMVI US net revenue $152.9M up 84% YoY.
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TG Therapeutics Q2 BRIUMVI revenue $138.8M (+91% YoY); raises FY guidance to $570-575M
Q2 2025 total revenue $141.1M; BRIUMVI U.S. net sales $138.8M, up 91% YoY vs $72.6M.
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TG Therapeutics Q1 BRIUMVI sales $119.7M (+137% YoY); raises FY revenue guidance
Q1 2025 BRIUMVI U.S. net revenue $119.7M vs $50.5M YoY, up ~137%.
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Q4 2024 BRIUMVI U.S. net revenue $103.6M; full year $310M, representing ~250% YoY growth.
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TG Therapeutics Prelim. Q4 BRIUMVI Rev $103.6M; FY2025 US Revenue Target $525M
Preliminary Q4 2024 BRIUMVI U.S. net product revenue $103.6M; full year 2024 $310M.
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TG Therapeutics Q3 BRIUMVI revenue $83.3M, raises FY2024 guidance to $300-$305M
BRIUMVI Q3 U.S. net sales $83.3M, up 15% QoQ and 230% YoY; full-year target raised to $300-$305M.
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TG Therapeutics Q2 BRIUMVI rev $72.6M, raises guidance; $250M credit facility; material weakness
Q2 BRIUMVI net revenue $72.6M (+350% YoY); net income $6.9M vs loss $47.6M.
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Shareholders approved increasing authorized common stock from 175M to 190M (73.8M for, 36.3M against).
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TG Therapeutics Q1 BRIUMVI revenue $50.5M, raises FY guidance to $270-290M
BRIUMVI U.S. net revenue $50.5M in Q1 2024, >25% QoQ growth; total revenue $63.5M includes $12.5M EU launch milestone.
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TG Therapeutics reports Q4 2023 BRIUMVI net revenue $39.9M; 2024 target $220-260M
BRIUMVI U.S. net revenue $39.9M in Q4 2023, $88.8M for full year 2023.
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Upfront payment to Precision: $7.5M ($5.25M cash + $2.25M equity); deferred $2.5M equity; up to $288M milestone payments plus high-single-digit to low-double-digit royalties.
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TG Therapeutics Q3 total net revenue $165.8M; BRIUMVI net sales $25.1M, net income $113.9M
BRIUMVI net sales $25.1M in Q3; ~$48.9M cumulative since launch; ~2,200 prescriptions from 500+ providers.
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TG Therapeutics announces $645M ex-US BRIUMVI deal with Neuraxpharm; Q2 net sales $16M
Upfront cash payment $140M plus $12.5M at first European launch; total deal up to $645M with milestones and double-digit royalties up to 30%.
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TG Therapeutics reports Q1 BRIUMVI net sales of $7.8M in first partial launch quarter
BRIUMVI net sales $7.8M for Q1 2023; over 400 prescriptions from 165+ HCPs at 125+ centers.
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TG Therapeutics reports Q4 2022 net loss of $53M; launches BRIUMVI for RMS
Net loss of $53.0M for Q4 2022, compared to $93.3M loss in Q4 2021; full year net loss $198.3M vs $348.1M.
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FDA approves TG Therapeutics' BRIUMVI for relapsing multiple sclerosis; launch expected Q1 2023
Approval based on ULTIMATE I & II Phase 3 trials showing annualized relapse rate reduction of 59% and 49% vs teriflunomide.
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TG Therapeutics reports Q3 net loss of $35.8M; ublituximab PDUFA set for Dec 28, 2022
Net loss of $35.8M for Q3 2022 vs $85.6M in Q3 2021; nine-month net loss of $145.3M.
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TG Therapeutics Q2 net loss $40.5M, down from $78.5M YoY; cash $231.8M
Net loss of $40.5M in Q2 2022 vs $78.5M in Q2 2021; six-month loss $109.5M vs $169.1M.
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TG Therapeutics withdraws BLA/sNDA for U2 in CLL/SLL; pulls UKONIQ from sale
Voluntarily withdrew BLA/sNDA for U2 (ublituximab + umbralisib) for CLL/SLL based on updated OS data imbalance favoring control arm.
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TG Therapeutics Q4 net loss $93.3M; UKONIQ revenue $2.3M; FDA partial hold on U2
Net loss Q4 2021 $93.3M ($88.2M Q4 2020); full year net loss $348.1M ($279.4M 2020).
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Updated OS hazard ratio improved vs preliminary 1.23; still not statistically significant (Sep 2021 cutoff).
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TG Therapeutics expands credit facility to $200M, extends maturity to 2026
Loan increased from $60M to $200M; initial $70M drawn, $7.8M used to refinance existing balance.
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FDA to hold ODAC meeting for TG Therapeutics' U2 BLA; PDUFA date likely extended
FDA notified TG Therapeutics it will host an ODAC meeting for the U2 BLA/sNDA for CLL/SLL.
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TG Therapeutics Q3 net loss $85.6M; UKONIQ revenue $2.0M; ublituximab BLA for RMS submitted
Net loss $85.6M Q3, $254.8M nine months; ex-stock comp net loss $71.6M and $207.8M.
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TG Therapeutics Q2 net loss $78.5M; UKONIQ revenue $1.5M; U2 PDUFA March 2022
Net loss $78.5M for Q2 2021, up from $52.9M in Q2 2020; ex-stock comp net loss ~$62.2M.
Earnings & guidance
Materiality & sentiment trend
Max materiality 0.90 · Median 0.78 · Most common event earnings