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Protara Q2 net loss $21.7M; guides ADVANCED-2 enrollment completion, THRIVE-3 interim results to 4Q 2026
Q2 2026 net loss of $21.7M ($0.36/share) vs. $15.0M ($0.35/share) in Q2 2025.
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Protara reports 68% six-month CR rate in TARA-002 trial; triggers warrant exercise period
Six-month complete response (CR) rate of 68.0% in 25 BCG-unresponsive NMIBC patients in Phase 2 ADVANCED-2 trial.
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Protara Therapeutics Q4 net loss $17.3M; TARA-002 shows 68% CR in BCG-Unresponsive NMIBC
Net loss Q4 2025: $17.3M ($0.37/share); FY2025: $57.4M ($1.34/share).
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TARA-002 shows 68% CR at 6 months in BCG-unresponsive NMIBC; no Grade 3+ TRAEs
BCG-Unresponsive cohort: CR rate 68.2% at 6 months (15/22), 33.3% at 12 months (5/15); 61.5% re-induction conversion.
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Protara closes full underwriters' option, gross proceeds ~$86.3M from offering
Closed full exercise of underwriters' option for 1,956,521 shares at $5.75/share on Dec 15, 2025.
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Protara Therapeutics prices public offering of 13M shares at $5.75 for $75M gross proceeds
Priced 13,043,479 common shares at $5.75 per share; gross proceeds ~$75M before fees.
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Protara reports 72% CR for TARA-002 in BCG-Naïve NMIBC; FDA backs registrational path
CR at any time 72% (21/29); 69% at 6 months, 50% at 12 months in BCG-Naïve NMIBC.
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Protara TARA-002 STARBORN-1: 100% clinical success in evaluable patients
8/8 evaluable patients (100%) achieved clinical success at eight-week assessment.
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Protara Therapeutics Q3 net loss $13.3M; cash runway into mid-2027; key trial data readouts on track
Net loss of $13.3M ($0.31 per share) vs $11.2M ($0.50 per share) in Q3 2024.
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Protara Q2 net loss $15M; cash $145.6M into mid-2027; key trial readouts set
Q2 2025 net loss $15.0M ($0.35/shr) vs $9.5M ($0.45/shr) in Q2 2024; R&D spend up to $10.8M.
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Protara Therapeutics Q1 2025 net loss $11.9M; TARA-002 100% CR in BCG-Unresponsive cohort
Cash, cash equivalents and investments total $157.5M as of Mar 31, 2025; expected to fund operations into 2027.
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Protara reports 100% CR at any time in BCG-unresponsive NMIBC; 67% at 12 months
BCG-Unresponsive: 100% CR at any time (5/5), 67% at 12 months (2/3) as of April 16, 2025 cutoff.
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Protara Q4 net loss $12.8M, cash $170M; ADVANCED-2 12-month data by mid-2025
Cash and equivalents $170.3M as of Dec 31, 2024, funded into 2027 after $100M public offering.
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Protara reports positive TARA-002 NMIBC data; expects key milestones in 2025; cash runway into 2027
TARA-002 in NMIBC: 72% CR at six months, 70% at any time; 100% maintained CR from 3 to 6 months; no Grade 2+ TRAEs.
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Protara Therapeutics raises $100M in public offering to fund TARA-002 clinical development
Gross proceeds of ~$100M from offering of 13.69M shares and 2.33M pre-funded warrants at $6.25/share.
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Protara TARA-002 shows 72% CR at 6 months in NMIBC Phase 2; 100% in BCG-unresponsive
72% (13/18) landmark complete response rate at 6 months across BCG exposures; 70% (14/20) at any time.
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Protara Therapeutics reports Q3 2024 net loss of $11.2M; cash $81.5M; pipeline on track
Net loss $11.2M ($0.50 per share) vs $9.9M ($0.87) in Q3 2023; no revenue.
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Protara Therapeutics Q2 net loss $9.5M; cash $89.6M; pipeline milestones on track
Net loss $9.5M ($0.45/share) vs $11.3M ($1.00/share) in Q2 2023; R&D expenses decreased to $6.4M.
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Protara Therapeutics Q1 net loss $11.1M; cash runway into 2026 after $42M private placement
Q1 net loss $11.1M ($0.97/sh) vs $9.0M ($0.80/sh) YoY; R&D spend rose to $7.7M from $5.1M.
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Protara raises ~$45M in private placement; reports positive TARA-002 data and FDA alignment for IV Choline Chloride
Private placement: gross proceeds ~$45M from 9.14M shares and 1.7M pre-funded warrants at $4.15; common warrants exercisable at $5.25.
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Protara CMO Jathin Bandari resigns effective April 11; interim oversight assigned
CMO Jathin Bandari resigns effective April 11, 2024 to explore academic opportunities; consulting through July 11.
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Protara reports Q4 net loss of $10.2M; cash $65.6M; TARA-002 data milestones in 2024
Net loss Q4 2023: $10.2M ($0.90/share); full-year net loss $40.4M ($3.57/share).
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Protara Q3 net loss $9.9M; cash $74M; TARA-002 trials advance with results expected 1H24
Q3 2023 net loss of $9.9M ($0.87/shr) vs $7.7M ($0.68/shr) in Q3 2022.
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Protara Q2 net loss $11.3M; TARA-002 trials on track; cash runway into 2025
Net loss Q2 2023: $11.3M ($1.00/share) vs $8.5M ($0.76) in Q2 2022
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Protara reports Q1 net loss $9.0M; plans Phase 2 trials for TARA-002 in NMIBC and LMs
Cash, equivalents and restricted cash $89.5M at March 31, 2023; funding expected into 2025.
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Protara reports positive Phase 1a data for TARA-002 in NMIBC; plans Phase 2 trial in 2H2023
TARA-002 well tolerated at all three doses; no dose-limiting toxicities; 40KE dose selected for further trials.
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Protara confirms no material SVB exposure; cash runway into 2025 unchanged
$102.3M cash equivalents invested in short-term treasury/corporate bonds, not SVB.
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Protara Q4 net loss $39.0M; cash $102.3M; TARA-002 data expected Q2 2023
Net loss Q4 2022: $39.0M ($3.46 per share) vs $10.2M ($0.91) in Q4 2021; includes $29.5M goodwill impairment.
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Protara Q3 net loss $7.7M; cash $107.1M; TARA-002 trials progressing
Net loss of $7.7M ($0.68/share) vs. $10.8M ($0.96) in Q3 2021; includes $1.4M stock-based compensation.
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Protara Therapeutics appoints Hannah Fry as Controller and CEO as principal financial officer after CFO departure
Blaine Davis departed as CFO on July 15, 2022.
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Protara Therapeutics CFO Blaine Davis to depart July 15, 2022
CFO Blaine Davis leaving to pursue other opportunities, effective July 15, 2022; resignation not due to disagreements.
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Protara Therapeutics Q1 2022 net loss narrows to $10.8M; cash $118.5M funds into mid-2024
Net loss of $10.8M ($0.96/share) versus $13.5M ($1.20/share) in Q1 2021.
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Protara Therapeutics reports Q4 net loss of $10.2M; cash $130.7M funds operations into mid-2024
Net loss for Q4 2021 was $10.2M ($0.91 loss per share); full year net loss $47.3M ($4.21 loss per share).
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Protara Therapeutics CMO Departs; Jathin Bandari Named Interim CMO
Martín Sebastian Olivo, M.D., left as Chief Medical Officer effective Oct 15, 2021; will serve as consultant through Nov 22, 2021.
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Protara Therapeutics receives FDA IND clearance for TARA-002 in non-muscle invasive bladder cancer
FDA cleared IND for TARA-002, an investigational cell-based therapy for NMIBC.