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Protara Q2 net loss $21.7M; guides ADVANCED-2 enrollment completion, THRIVE-3 interim results to 4Q 2026
Q2 2026 net loss of $21.7M ($0.36/share) vs. $15.0M ($0.35/share) in Q2 2025.
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Protara Therapeutics CMO Leonardo Viana Nicacio resigns effective June 26, 2026
Leonardo Viana Nicacio, M.D., resigned as Chief Medical Officer to pursue other opportunities.
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Protara shareholders vote to double authorized shares to 200M at annual meeting
Authorized common stock increased from 100M to 200M shares; 42.4M for, 2.7M against.
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Protara Therapeutics Reports Q1 2026 Results, Advances TARA-002 Programs in LMs and NMIBC
Cash and cash equivalents and investments of $177.4 million as of March 31, 2026, expected to fund operations into 2028.
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Protara reports 68% six-month CR rate in TARA-002 trial; triggers warrant exercise period
Six-month complete response (CR) rate of 68.0% in 25 BCG-unresponsive NMIBC patients in Phase 2 ADVANCED-2 trial.
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Protara Therapeutics Q4 net loss $17.3M; TARA-002 shows 68% CR in BCG-Unresponsive NMIBC
Net loss Q4 2025: $17.3M ($0.37/share); FY2025: $57.4M ($1.34/share).
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TARA-002 shows 68% CR at 6 months in BCG-unresponsive NMIBC; no Grade 3+ TRAEs
BCG-Unresponsive cohort: CR rate 68.2% at 6 months (15/22), 33.3% at 12 months (5/15); 61.5% re-induction conversion.
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Protara closes full underwriters' option, gross proceeds ~$86.3M from offering
Closed full exercise of underwriters' option for 1,956,521 shares at $5.75/share on Dec 15, 2025.
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Protara Therapeutics prices public offering of 13M shares at $5.75 for $75M gross proceeds
Priced 13,043,479 common shares at $5.75 per share; gross proceeds ~$75M before fees.
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Protara reports 72% CR for TARA-002 in BCG-Naïve NMIBC; FDA backs registrational path
CR at any time 72% (21/29); 69% at 6 months, 50% at 12 months in BCG-Naïve NMIBC.
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Protara TARA-002 STARBORN-1: 100% clinical success in evaluable patients
8/8 evaluable patients (100%) achieved clinical success at eight-week assessment.
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Protara Therapeutics Q3 net loss $13.3M; cash runway into mid-2027; key trial data readouts on track
Net loss of $13.3M ($0.31 per share) vs $11.2M ($0.50 per share) in Q3 2024.
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Protara Q2 net loss $15M; cash $145.6M into mid-2027; key trial readouts set
Q2 2025 net loss $15.0M ($0.35/shr) vs $9.5M ($0.45/shr) in Q2 2024; R&D spend up to $10.8M.
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Protara Therapeutics stockholders elect directors and approve equity plan at 2025 annual meeting
Stockholders elected Luke Beshar, Roger Garceau, and Gregory Sargen as Class II directors with 17.7M, 22.1M, and 22.1M votes for, respectively.
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Protara Therapeutics Q1 2025 net loss $11.9M; TARA-002 100% CR in BCG-Unresponsive cohort
Cash, cash equivalents and investments total $157.5M as of Mar 31, 2025; expected to fund operations into 2027.
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Protara reports 100% CR at any time in BCG-unresponsive NMIBC; 67% at 12 months
BCG-Unresponsive: 100% CR at any time (5/5), 67% at 12 months (2/3) as of April 16, 2025 cutoff.
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Protara Q4 net loss $12.8M, cash $170M; ADVANCED-2 12-month data by mid-2025
Cash and equivalents $170.3M as of Dec 31, 2024, funded into 2027 after $100M public offering.
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Protara reports positive TARA-002 NMIBC data; expects key milestones in 2025; cash runway into 2027
TARA-002 in NMIBC: 72% CR at six months, 70% at any time; 100% maintained CR from 3 to 6 months; no Grade 2+ TRAEs.
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Protara Therapeutics raises $100M in public offering to fund TARA-002 clinical development
Gross proceeds of ~$100M from offering of 13.69M shares and 2.33M pre-funded warrants at $6.25/share.
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Protara TARA-002 shows 72% CR at 6 months in NMIBC Phase 2; 100% in BCG-unresponsive
72% (13/18) landmark complete response rate at 6 months across BCG exposures; 70% (14/20) at any time.
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Protara Therapeutics reports Q3 2024 net loss of $11.2M; cash $81.5M; pipeline on track
Net loss $11.2M ($0.50 per share) vs $9.9M ($0.87) in Q3 2023; no revenue.
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Protara Therapeutics Q2 net loss $9.5M; cash $89.6M; pipeline milestones on track
Net loss $9.5M ($0.45/share) vs $11.3M ($1.00/share) in Q2 2023; R&D expenses decreased to $6.4M.
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Protara Therapeutics stockholders approve all five proposals at 2024 Annual Meeting
Class I directors elected: Jane Huang (9.66M for), Richard Levy (9.64M for), Michael Solomon (9.56M for); broker non-votes 3.81M.
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Protara Therapeutics Q1 net loss $11.1M; cash runway into 2026 after $42M private placement
Q1 net loss $11.1M ($0.97/sh) vs $9.0M ($0.80/sh) YoY; R&D spend rose to $7.7M from $5.1M.
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Protara raises ~$45M in private placement; reports positive TARA-002 data and FDA alignment for IV Choline Chloride
Private placement: gross proceeds ~$45M from 9.14M shares and 1.7M pre-funded warrants at $4.15; common warrants exercisable at $5.25.
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Protara CMO Jathin Bandari resigns effective April 11; interim oversight assigned
CMO Jathin Bandari resigns effective April 11, 2024 to explore academic opportunities; consulting through July 11.
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Protara reports Q4 net loss of $10.2M; cash $65.6M; TARA-002 data milestones in 2024
Net loss Q4 2023: $10.2M ($0.90/share); full-year net loss $40.4M ($3.57/share).
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Protara Q3 net loss $9.9M; cash $74M; TARA-002 trials advance with results expected 1H24
Q3 2023 net loss of $9.9M ($0.87/shr) vs $7.7M ($0.68/shr) in Q3 2022.
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Protara Q2 net loss $11.3M; TARA-002 trials on track; cash runway into 2025
Net loss Q2 2023: $11.3M ($1.00/share) vs $8.5M ($0.76) in Q2 2022
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Protara Therapeutics annual meeting: all proposals approved by shareholders
Class III directors elected: Shefferman 5.68M for, Flannelly 5.63M, Smith 5.66M; 2.26M broker non-votes each.
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Protara reports Q1 net loss $9.0M; plans Phase 2 trials for TARA-002 in NMIBC and LMs
Cash, equivalents and restricted cash $89.5M at March 31, 2023; funding expected into 2025.
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Protara gets FDA clearance to start Phase 2 STARBORN-1 trial of TARA-002 for pediatric lymphatic malformations
FDA cleared the Phase 2 STARBORN-1 trial of TARA-002 (cell-based immunopotentiator) in pediatric patients with lymphatic malformations.
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Protara reports positive Phase 1a data for TARA-002 in NMIBC; plans Phase 2 trial in 2H2023
TARA-002 well tolerated at all three doses; no dose-limiting toxicities; 40KE dose selected for further trials.
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Protara confirms no material SVB exposure; cash runway into 2025 unchanged
$102.3M cash equivalents invested in short-term treasury/corporate bonds, not SVB.
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Protara Q4 net loss $39.0M; cash $102.3M; TARA-002 data expected Q2 2023
Net loss Q4 2022: $39.0M ($3.46 per share) vs $10.2M ($0.91) in Q4 2021; includes $29.5M goodwill impairment.
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Protara Therapeutics appoints Patrick Fabbio as CFO effective Jan 30, 2023
Patrick Fabbio appointed CFO, replacing interim CFO Jesse Shefferman (CEO).
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Protara Therapeutics posts corporate presentation; content not detailed in filing
Presentation filed as Exhibit 99.1 and posted on IR page on January 5, 2023.
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Protara Q3 net loss $7.7M; cash $107.1M; TARA-002 trials progressing
Net loss of $7.7M ($0.68/share) vs. $10.8M ($0.96) in Q3 2021; includes $1.4M stock-based compensation.
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Protara Therapeutics Q2 2022 net loss $8.5M ($0.80/share); cash $112.8M
Net loss of $8.5M ($0.80 per share) vs $12.8M ($1.14) in Q2 2021.
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Protara Therapeutics appoints Hannah Fry as Controller and CEO as principal financial officer after CFO departure
Blaine Davis departed as CFO on July 15, 2022.
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Protara Therapeutics CFO Blaine Davis to depart July 15, 2022
CFO Blaine Davis leaving to pursue other opportunities, effective July 15, 2022; resignation not due to disagreements.
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Protara Therapeutics shareholders elect three directors, ratify auditor, approve say-on-pay at 2022 annual meeting
Elected Luke Beshar, Roger Garceau, and Gregory Sargen as Class II directors to serve until 2025 annual meeting.
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Protara Therapeutics Q1 2022 net loss narrows to $10.8M; cash $118.5M funds into mid-2024
Net loss of $10.8M ($0.96/share) versus $13.5M ($1.20/share) in Q1 2021.
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Protara Therapeutics reports Q4 net loss of $10.2M; cash $130.7M funds operations into mid-2024
Net loss for Q4 2021 was $10.2M ($0.91 loss per share); full year net loss $47.3M ($4.21 loss per share).
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Protara Therapeutics appoints Jathin Bandari as Chief Medical Officer
Dr. Bandari, previously Interim CMO, appointed permanent CMO effective Jan 10, 2022.
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Protara Therapeutics reports Q3 2021 net loss of $10.8M; FDA clears IND for TARA-002 in NMIBC
Net loss $10.8M ($0.96/sh) vs $8.0M ($1.26/sh) in Q3 2020; R&D expense $4.1M (up from $2.8M), G&A $6.7M (up from $5.3M).
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Protara Therapeutics CMO Departs; Jathin Bandari Named Interim CMO
Martín Sebastian Olivo, M.D., left as Chief Medical Officer effective Oct 15, 2021; will serve as consultant through Nov 22, 2021.
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Protara Therapeutics receives FDA IND clearance for TARA-002 in non-muscle invasive bladder cancer
FDA cleared IND for TARA-002, an investigational cell-based therapy for NMIBC.
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Protara Q2 net loss $12.8M; cash $145M; on track for TARA-002 IND by year-end
Cash $145M; net loss $12.8M ($1.14/sh) vs $7.1M ($1.22/sh) in Q2 2020.