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Neumora appoints Joshua Pinto as CEO, narrows Q2 net loss to $43.1M
Joshua Pinto named CEO and Board member; Paul Berns becomes Executive Chair, effective Aug 14, 2026.
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Neumora Therapeutics reports favorable NMRA-215 toxicology results, plans IND in Q4 2026
Repeat 13-week rat toxicology study (162 animals) showed no unexpected adverse findings, resolving prior concerns from a study with 5 of 142 animals affected.
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Neumora discontinues navacaprant after Phase 3 MDD failures; cuts workforce 35%
Navacaprant failed primary endpoint in KOASTAL-2 (p=0.813) and KOASTAL-3 (p=0.480); development discontinued.
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Neumora Therapeutics annual meeting elects directors, ratifies auditor, approves executive compensation
Directors Paul L. Berns, Matthew Fust, David Piacquad elected with ~126M, ~125M, ~127M votes for, respectively; ~25M broker non-votes.
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Neumora Q1 net loss $53.5M, cash $147M; navacaprant data on track for Q2 2026
Net loss of $53.5M for Q1 2026, improved from $68.0M in Q1 2025.
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Neumora FY2025 net loss $236.9M; NMRA-511 positive data; NMRA-215 delayed to Q1 2027; cash to Q3 2027
Cash $182.5M; FY net loss $236.9M; R&D $176.1M, G&A $60.1M; cash runway into Q3 2027.
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Neumora Therapeutics releases corporate presentation at Guggenheim summit; no material details disclosed
Presentation dated February 2026 made available for Guggenheim Emerging Outlook: Biotech Summit.
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Neumora Therapeutics furnishes corporate presentation for J.P. Morgan conference; full content not disclosed in filing
Corporate presentation made available under Item 7.01, not filed for SEC purposes.
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NMRA-511 Phase 1b shows clinically meaningful effect in AD agitation; navacaprant readout in Q2 2026
NMRA-511 Phase 1b: 15.7-point mean CMAI reduction, no somnolence/sedation; plan higher doses and Phase 2/3 in 2026
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K2HV converts $2.5M loan principal into 2.85M NMRA shares at $0.8774/share
K2 HealthVentures converted $2.5M of term-loan principal into 2,849,327 common shares of NMRA at $0.8774/share.
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Neumora Q3 net loss $56.8M; cash $171.5M; pipeline updates on NMRA-215, M4 PAMs, NMRA-511
Net loss of $56.8M for Q3 2025 vs $72.5M in Q3 2024; R&D expense down to $40.5M from $60.6M.
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Neumora reports NMRA-215 preclinical data: up to 19% monotherapy weight loss, 26% with semaglutide
NMRA-215 showed class-leading 19% weight loss as monotherapy with semaglutide-like induction in DIO mice.
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Neumora starts Phase 1 study of second M4 PAM, NMRA-898; no convulsions in preclinical
Initiated Phase 1 SAD/MAD study of NMRA-898, an M4 positive allosteric modulator for schizophrenia and neuropsychiatric disorders.
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Neumora Q2 net loss $52.7M, cash $217.6M; advances NMRA-861 Phase 1, obesity lead for NMRA-215
Cash, equivalents and marketable securities of $217.6M as of June 30, 2025; expected to fund operations into 2027.
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Neumora Therapeutics stockholders elect directors, approve option repricing and reverse split at 2025 annual meeting
Elected Alaa Halawa (105,795,914 votes for) and Maykin Ho (114,262,481 votes for) as Class II directors.
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Neumora receives Nasdaq minimum bid price deficiency notice; has until Nov 10, 2025 to cure
Nasdaq notified Neumora on May 14, 2025 that its stock failed to meet the $1.00 minimum bid price requirement.
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Neumora Q1 net loss $68M, secures $125M venture debt; navacaprant Ph3 data in 2026
Net loss $68.0M in Q1 2025, up from $53.7M in Q1 2024; R&D expense $52.2M (incl. $6.3M final Amgen costs).
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Neumora revises stock option repricing to use closing price on May 28, 2025 annual meeting date
Originally repriced using Feb 13, 2025 closing price; revised on Apr 7, 2025 to use closing price on scheduled annual meeting date (May 28, 2025).
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Neumora modifies KOASTAL-2/-3 MDD studies, delays data to 2026; R&D head departs
KOASTAL-2/-3 paused, resume March 2025; topline data from KOASTAL-3 in Q1 2026 and -2 in Q2 2026.
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Neumora Therapeutics appoints Paul Berns as Chairman & CEO, Gosebruch exits
Henry Gosebruch separates as CEO; receives 12-month base salary, 2025 target bonus, 18-month COBRA, 2024 bonus, and 12-month option exercise period.
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Founder Berns becomes CEO as Gosebruch departs; option repricing approved
Paul L. Berns transitions from executive chair to CEO & chairman, effective Feb 14, 2025.
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Neumora Therapeutics presents at J.P. Morgan Healthcare Conference; no specific data disclosed in filing exhibit
Corporate presentation made available for J.P. Morgan Healthcare Conference on Jan 13, 2025.
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Neumora's Phase 3 KOASTAL-1 study of navacaprant fails primary endpoint in MDD
Primary endpoint MADRS total score change at Week 6: -12.5 for both navacaprant and placebo (p=0.993); no statistical improvement.
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Neumora Q3 net loss $72.5M; cash $341.3M; Ph3 MDD data around end-2024
Cash and marketable securities $341.3M; operations funded into mid-2026.
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Neumora Q2 net loss $58.7M; Phase 3 MDD data on track for Q4 2024
Cash $371.6M as of June 30, 2024, expected to fund operations into 2026.
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Neumora stockholders elect Gosebruch and Burow as Class I directors, ratify EY as auditor
Henry O. Gosebruch elected with 88,190,874 votes for, 2,313,739 withheld, and 12,544,469 broker non-votes.
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Neumora Q1 net loss $53.7M; navacaprant Phase 3 MDD data on track for Q4 2024; NMRA-266 clinical hold with FDA
Net loss of $53.7M in Q1 2024 vs $35.6M in Q1 2023; R&D expense $45.8M, G&A $14.3M.
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Neumora's NMRA-266 Phase 1 placed on clinical hold by FDA after rabbit convulsion data
FDA placed clinical hold on NMRA-266 Phase 1 trial due to preclinical convulsions in rabbits.
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Neumora reports Q4 2023 net loss of $108.7M; cash $463.8M into 2026
Net loss Q4 2023: $108.7M vs $28.1M in Q4 2022; full year net loss $235.9M vs $130.9M.
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Neumora makes corporate presentation available at J.P. Morgan Healthcare Conference
Presentation furnished as Exhibit 99.1; no financial or pipeline specifics provided in the filing text.
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Neumora receives FDA IND clearance for NMRA-266; starts Phase 1
NMRA-266 is a positive allosteric modulator of M4 muscarinic receptor, licensed from Vanderbilt University.
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Neumora Q3 net loss $53.0M; cash $519.5M; navacaprant Phase 3 on track
Net loss of $53.0M in Q3 2023 vs. $29.3M in Q3 2022, driven by higher R&D costs ($41.6M vs. $22.5M).
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Neumora Therapeutics closes IPO: 14.71M shares at $17, gross proceeds ~$250.1M
Completed IPO of 14,710,000 shares of common stock at $17.00 per share on September 19, 2023.