Brigette Roberts
Brigette Roberts, M.D., was appointed to the Board as a Class III director.
Highest-materiality recent filing
Quince reports positive Phase 2a LAM-001 data in PH-ILD; 6MWD +67.4m, PVR -33.9%
Phase 2a open-label trial in PH-ILD (n=4 evaluable) on stable treprostinil showed 6MWD increase of 67.4 meters and PVR reduction of 33.9% at 24 weeks.
Quince acquires Orphai in reverse merger; raises $115M PIPE; appoints Dr. Roberts
Acquisition closed May 18; Quince issued 3.26M shares and 67K Series C Preferred to Orphai holders.
Quince settles $16.4M EIB debt for $5.5M, eliminates debt overhang
Paid $5.5M to settle ~$16.4M in EIB debt obligations, a discount of roughly $10.9M.
Quince Therapeutics receives two Nasdaq deficiency notices with 180-day cure periods
Bid Price Notice: common stock closing bid below $1.00 for 30 consecutive business days; cure by Sept 14, 2026.
Quince Therapeutics reports $5.8M cash, $16.4M debt; engages LifeSci Capital for reverse merger
As of Dec 31, 2025, cash and short-term investments total $17.7M; EIB Loan outstanding $16.4M.
Five directors resign from Quince Therapeutics board effective immediately
Directors Rajiv Patni, Luca Benatti, Margi McLoughlin, Una Ryan, and June Bray resigned on Jan 30, 2026.
Quince Therapeutics Phase 3 NEAT trial misses primary endpoint; eDSP development halted
Primary endpoint RmICARS p=0.0851; mean change from baseline -1.30 vs placebo.
Quince Therapeutics Q3 net loss $13.3M; Phase 3 NEAT trial on track for Q1 2026 data
Cash, cash equivalents, and short-term investments of $26.3M; runway expected through Q2 2026.
Quince completes Phase 3 NEAT enrollment; Q2 net loss $16.1M
Pivotal Phase 3 NEAT trial enrollment completed with 105 participants; topline results expected Q1 2026.
Quince completes Phase 3 NEAT enrollment with 105 patients; topline results Q1 2026
Enrolled 105 participants total; 83 in primary analysis (ages 6-9), 22 aged 10+.
Quince raises $11.5M in private placement of stock and warrants; management participates
Sold 6,671,928 shares, 2M pre-funded warrants, and 8,671,928 common warrants for $11.5M gross proceeds.
Brigette Roberts, M.D., was appointed to the Board as a Class III director.
Dr. Roberts was also appointed as the Chief of Corporate Affairs of the Company.
Max materiality 1.00 · Median 0.70 · Most common event other_material