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Hepion Pharma CEO Kaouthar Lbiati resigns; Gary Stetz named interim CEO
CEO Dr. Kaouthar Lbiati resigned effective March 16, 2026, for personal reasons.
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Hepion Pharmaceuticals names Kaouthar Lbiati CEO effective Jan 8, 2026; salary $350K
Dr. Kaouthar Lbiati appointed CEO effective Jan 8, 2026, per Board approval on Jan 13, 2026.
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Hepion Pharmaceuticals CFO John Brancaccio resigns; interim CFO named
John Brancaccio resigned as CFO and director effective June 30, 2025, for personal reasons.
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Hepion shareholders reject reverse stock split amendment at 2025 annual meeting
Reverse stock split proposal (1:5 to 1:20) failed with 2.25M for, 3.70M against; not approved.
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Hepion appoints director Kaouthar Lbiati as interim CEO effective June 16
Dr. Kaouthar Lbiati, a board member since June 2022, appointed interim CEO effective June 16, 2025.
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Hepion sells Rencofilstat assets to Panetta for nominal fee; stockholders get CVR milestones
Sold all patent assets, knowhow, clinical data, and drug product for Rencofilstat to Panetta Partners for nominal amount.
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Hepion delisted from Nasdaq; pivots to diagnostics via New Day license
Received Nasdaq delisting notice for failing to maintain $1.00 bid price and being deemed a public shell; trading suspended May 13, 2025.
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Nasdaq deems Hepion a 'public shell' as additional delisting basis; hearing April 29
Received Nasdaq notice on April 15, 2025, alleging company is a 'public shell' and continued listing unwarranted.
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Hepion receives Nasdaq delisting notice as bid price falls below $0.10 for 10 days
Stock closed below $0.10 for 10 consecutive business days triggering the Low Priced Stocks Rule.
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Hepion shareholders approve reverse stock split (1:10-1:50) at annual meeting
All four director nominees elected (Brancaccio, Block, Lbiati, Purcell) with majority 'For' votes.
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Hepion Pharma receives Nasdaq delisting notice for failure to hold annual meeting; 45 days to submit compliance plan
Notice dated January 14, 2025 from Nasdaq for failing to hold annual shareholders' meeting within 12 months of fiscal year end.
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Hepion terminates merger with Pharma Two B; special meeting cancelled
Merger Agreement with Pharma Two B Ltd. terminated mutually on Dec 10, 2024.
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Hepion Pharma receives Nasdaq delisting notice due to stockholder deficit and failure to meet listing alternatives
Stockholders' deficit of ($406,685) as of Sept 30, 2024 triggers Nasdaq Listing Rule non-compliance.
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Hepion Pharmaceuticals receives Nasdaq deficiency notice for bid price below $1.00
Notice received Sept. 3, 2024; bid price below $1.00 for 30 consecutive business days.
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Hepion Pharma's interim CEO/CFO resigns; executive chairman takes over
John Cavan departed as interim CEO and CFO on August 5, 2024 for personal reasons.
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Hepion Pharmaceuticals enters definitive merger agreement with Pharma Two B Ltd., expects Q4 2024 close
Hepion will merge with Pharma Two B Ltd.; existing Hepion shareholders receive ordinary shares of Parent.
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Hepion raises $2.06M via warrant inducement, reduces exercise prices and issues new warrants
Holders of 980,393 Series B warrants will exercise at reduced price of $2.10/share, raising ~$2.06M gross proceeds.
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Hepion Pharmaceuticals dismisses BDO, appoints Grassi as new auditor
BDO dismissed as independent auditor effective Jan 1, 2024; Grassi Advisors engaged to audit FY 2023 financials.
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Hepion CEO resigns, interim CEO named; restructuring plan to cut costs 60%
Dr. Robert Foster resigns as CEO and director for personal reasons, effective immediately.
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Hepion Pharmaceuticals raises $5.0M in registered direct offering with warrants
Gross proceeds $5.0M from sale of 980,393 shares (or equivalents) at $5.10/share plus warrants.
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Hepion Pharmaceuticals enters $24M ATM equity offering with Cantor Fitzgerald
ATM sales agreement with Cantor Fitzgerald allows Hepion to sell up to $24M of common stock at market prices.
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Hepion Phase 2 ALTITUDE-NASH trial meets primary endpoint with rencofilstat 225 mg improving liver function
Phase 2 trial met primary endpoint: 225 mg rencofilstat reduced DSI by 1.62 units (p<0.05) and SHUNT by 2.8% (p<0.05).
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Hepion Pharmaceuticals Raises $20M via Private Placement of Convertible Preferred Stock
Offering includes 1,900,000 Series F and 100,000 Series G shares at $9.50 each.
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Hepion receives Nasdaq delisting notice for bid price below $1.00 per share
Notice received June 3, 2022; stock continues trading under symbol HEPA.
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Hepion reports positive Phase 2a AMBITION NASH data; plans three Phase 2/2b trials starting Q3 2022
Phase 2a AMBITION NASH trial met primary endpoints: safety, tolerability, PK; no serious adverse events.
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Hepion provides pipeline update: Rencofilstat Phase 2a NASH trial positive; Phase 2b and HCC trials underway
Phase 2a NASH trial (AMBITION) met safety endpoints; showed ALT and Pro-C3 reductions over 28 days.
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Hepion Pharma gets FDA IND clearance for CRV431 in liver cancer (HCC), enabling direct Phase 2 start
FDA accepted IND for CRV431 for hepatocellular carcinoma; allows Phase 2 trial to begin without Phase 1.