Highest-materiality recent filing
Senti Biosciences issues $10M convertible notes to Celadon; discloses potential merger with $60M CVR
$10M senior secured convertible notes sold to Celadon Partners; maturity 6 months, 12% default interest rate on event of default.
Net loss $4.2M ($0.14/share) vs $14.1M year ago; cash $8.9M as of March 31, 2026.
Senti Biosciences enters $40M convertible note agreement with Celadon; initial $10M tranche
Celadon Partners, largest stockholder, commits up to $40M via Senior Secured Convertible Notes; first tranche $10M.
Senti Bio FY2025 net loss $61.4M; SENTI-202 gets RMAT, Phase 1 data encouraging
Net loss $61.4M for FY2025 ($2.73/share); Q4 loss $14.5M ($0.53/share).
Senti Bio reports SENTI-202 Phase 1 data: 50% ORR, 42% CR/CRh at RP2D; receives FDA RMAT designation
In 18 evaluable R/R AML patients, SENTI-202 achieved 50% ORR and 42% CR/CRh at RP2D; 100% of CRs MRD negative and median duration of CR 7.6 months.
Senti Bio Q3 net loss $18.1M; cash $12.2M; ASH data ahead
Cash and cash equivalents $12.2M as of Sep 30, 2025, down from $48.3M at Dec 31, 2024.
Senti Bio Q2 2025 net loss $14.7M; completes dose finding for SENTI-202 AML trial, RP2D confirmed
Net loss of $14.7M ($0.56 per share); cash $21.6M as of June 30, 2025, down from $48.3M at Dec 31, 2024.
Senti Bio receives FDA Orphan Drug Designation for SENTI-202 CAR NK therapy in AML
FDA granted Orphan Drug Designation to SENTI-202 for relapsed/refractory hematologic malignancies, including AML.
Senti Bio reports Q1 2025 net loss $14.1M; SENTI-202 Phase 1 shows 4 of 7 cCR with MRD negativity
Net loss of $14.1M ($1.41 per share) for Q1 2025; cash and equivalents $33.8M as of March 31.
SENTI-202 Phase 1 shows 5/7 ORR in R/R AML; RP2D set; cash $33.8M at Q1 2025
5 of 7 evaluable R/R AML patients achieved ORR (3 CR, 1 CRh, 1 MLFS); all cCR patients MRD-negative.
Filed Form S-3 to register up to $300M of common stock, preferred, debt, warrants, and units.
Senti Bio reports Q4 net loss $0.6M; two AML patients remain in remission from SENTI-202 trial
Q4 net loss $0.6M ($0.67/share); full year net loss $52.8M ($12.03/share).
Senti Bio appoints Jay Cross as CFO and Faraz Siddiqui as SVP Technical Operations
Jay Cross appointed CFO effective March 3, 2025; base salary $465k, annual target bonus 40%, sign-on bonus $50k repayable if leaving before 14 months.
Senti Biosciences CFO Yvonne Li departs; transition consultant through March 31
Yvonne Li's consulting agreement as Interim CFO expired Jan 31, 2025; she ceased as principal financial and accounting officer.
Senti Bio secures additional $11.5M from PIPE closing and CIRM grant; cash runway into 2026
Closed subsequent PIPE closing with Celadon Partners for additional ~$10M gross proceeds (4,444 Series A shares + warrants for 6,666,000 common shares); total PIPE now $47.6M.
Senti Bio reports 2 of 3 AML patients achieve MRD-negative CR in Phase 1 SENTI-202 trial
Two of three R/R AML patients at lowest dose (1.0B CAR+ NK cells) achieved CR with MRD negativity; both maintain remission (4+ and 3+ months).
Senti Biosciences raises up to $47.6M in Series A preferred stock and warrants private placement
Issued up to 21,157 shares of Series A Convertible Preferred at $2,250/share, with warrants for up to 31.7M common shares at $2.30.
Senti Bio Q3 net loss $28.9M; cash $10.5M; SENTI-202 data expected Q4 2024
Net loss $28.9M ($6.31 per share); R&D spend $8.7M (down from $9.1M YoY).
Senti Bio receives Nasdaq deficiency notice for audit committee composition
On Oct 22, 2024, Nasdaq notified Senti Bio that its audit committee has only two members, violating Listing Rule 5605(c)(2)(A).
Senti Bio Q2 net loss $11.2M; doses first patients in Phase 1 AML trial
Net loss of $11.2M ($2.45 per share) for Q2 2024; cash and equivalents $15.9M.
Senti Biosciences effectuates 1-for-10 reverse stock split effective July 17, 2024
Reverse stock split at 1-for-10 ratio approved by Board on July 10, 2024.
Senti Bio appoints Kanya Rajangam as President; CEO Lu remains CEO
Tim Lu stepped down as President effective May 14, 2024, but continues as CEO.
Senti Bio CFO Deborah Knobelman resigns; search for interim CFO underway
Deborah Knobelman, Ph.D., CFO, Treasurer and Head of Corp. Dev., resigned effective May 3, 2024.
On March 7, 2025, the Board of Directors (the “Board”) of Senti Biosciences, Inc. (the “Company”) approved the appointment of Feng Hsiung to the Board, pursuant to the terms of a letter agreement dated as of December 2, 2024, by and between the Company and Celadon Partners SPV 24.
Jay Cross was appointed as the Company’s Chief Financial Officer, effective as of March 3, 2025.
On January 31, 2025, Yvonne Li, the Consulting Agreement by and between Senti Biosciences, Inc. (the “Company”) and Yvonne Li, the Company’s Interim Chief Financial Officer, expired in accordance with its terms.
On December 2, 2024, upon the recommendation of its Nominating and Corporate Governance Committee, the Board unanimously appointed Frances D. Schulz to fill a newly created vacancy on the Board resulting from the resignation of Dr. Farokhzad, such appointment to be effective upon the initial closing of the Offering.
On November 25, 2024, Omid Farokhzad, M.D., a member of the Board and the Audit Committee of the Board, notified the Board of his resignation as a director of the Company and all committees thereof, effective November 25, 2024.
Kanya Rajangam, M.D., Ph.D., the Company's Head of Research and Development, and Chief Medical Officer, was appointed to serve as the President of the Company, effective as of May 14, 2024
Timothy Lu, M.D., Ph.D., Chief Executive Officer and President, stepped down as President
Yvonne Li was appointed as Interim Chief Financial Officer and will assume the duties of the Chief Financial Officer, effective May 4, 2024
Timothy Lu, M.D., Ph.D., the Chief Executive Officer and President of the Company, was appointed to serve as the interim principal financial officer and principal accounting officer of the Company, effective as of May 4, 2024
On April 23, 2024, Deborah Knobelman, Ph.D., the Chief Financial Officer, Treasurer and Head of Corporate Development of Senti Biosciences Inc. (“the Company”) and its principal financial officer and principal accounting officer, notified the Company of her decision to resign from her employment with the Company, effective May 3, 2024.
Max materiality 0.85 · Median 0.60 · Most common event other_material