Sohanya Cheng
On October 30, 2024, the Board elected Sohanya Cheng as a director of the Company, effective October 31, 2024.
Highest-materiality recent filing
Carisma voluntarily delisting from Nasdaq, terminating SEC reporting; appoints new CEO for wind-down
Board approved voluntary delisting from Nasdaq; Form 25 expected Dec 10; delisting effective 10 days later.
Carisma Therapeutics terminates CEO (eff. Nov 15) and CSO; three directors resign
CEO Steven Kelly terminated without cause, effective Nov 15, 2025; gets $624K severance plus $299,948 prorated bonus and health payments.
Carisma Therapeutics to be delisted from Nasdaq on Oct 13; expects to wind down operations
Received Nasdaq delisting letter; common stock suspended from trading effective Oct 13, 2025; no appeal planned.
Carisma terminates merger with OrthoCellix, receives $4M from Moderna, expects wind-down
Moderna pays $4M one-time to eliminate all future milestones, royalties, and research costs under the 2022 collaboration; licenses become fully paid-up and perpetual.
Carisma enters $5M subscription deal with Ocugen; Nasdaq deadline extended to Oct 21
Subscription agreement with Ocugen for $5M private placement as part of concurrent $25M financing.
Nasdaq notified Carisma on July 9, 2025 that failure to regain bid price compliance is an additional delisting basis.
Carisma to merge with OrthoCellix; pre-merger holders to own ~10% of combined company
Carisma (CARM) enters merger with Ocugen subsidiary OrthoCellix; Merger Sub to merge into OrthoCellix, which becomes wholly owned subsidiary.
Nasdaq Panel granted exception; listing transferred to Nasdaq Capital Market effective June 12, 2025.
Carisma receives Nasdaq delisting notice for MVLS, MVPHS, bid price non-compliance
Nasdaq notified Carisma on April 10, 2025, of delisting for failing to maintain $50M MVLS by April 8, 2025 compliance deadline.
Received Nasdaq notice on Jan 6, 2025 for non-compliance with minimum bid price of $1.00 per share.
Carisma Therapeutics appoints interim VP of Finance, principal accounting officer
Natalie McAndrew appointed interim VP of Finance effective Jan 1, 2025.
Carisma Therapeutics reduces workforce by 34%, terminates CFO, discontinues lead candidate CT-0525
Reduction of 23 employees (34% of workforce); expects ~$2.7M in one-time termination costs, substantially complete by Q1 2025.
Carisma Q3 net loss $12.7M; cash $26.9M; CT-0525 initial data expected Q1 2025
Net loss of $12.7M in Q3 2024 vs $21.4M in Q3 2023; R&D expenses fell to $11.3M from $19.6M.
Carisma Therapeutics receives Nasdaq deficiency notice for market value below $50M
Nasdaq notified Carisma on Oct 10, 2024 that MVLS fell below $50M minimum requirement.
Carisma Therapeutics Q2 2024 net loss $11.2M; CT-0525 data expected by year-end
Net loss improved to $11.2M in Q2 2024 from $19.9M in Q2 2023; R&D expenses declined to $15.3M.
Carisma reports 75% ctDNA reduction in HER2 3+ patients in Phase 1 CT-0508 trial
75% (6/8) evaluable HER2 3+ patients had ctDNA reduction (median 81%, range 33%-93%); no reduction in 5 HER2 2+ patients.
Terminated Manufacturing and Supply Agreement with Novartis for CT-0508; effective July 31, 2024.
Carisma nominates first in vivo CAR-M candidate under Moderna collab; $2M milestone triggered
Development candidate targets Glypican-3 for solid tumors, including hepatocellular carcinoma (HCC).
Carisma Therapeutics Q1 net loss $19.0M; cash $56.5M; lead candidate CT-0525 prioritized
Net loss $19.0M for Q1 2024 vs $24.6M in Q1 2023; R&D expenses $17.5M.
Carisma reports preliminary Phase 1 data for CT-0508; 40.7% target lesion reduction in monotherapy
In 14 monotherapy patients, 40.7% of target lesions reduced in size on ≥1 scan across all anatomic sites.
Carisma Therapeutics reports $86.9M net loss; prioritizes CT-0525, cuts workforce 37%
Cash of $77.6M as of Dec 31, 2023, expected to fund operations into Q3 2025 after restructuring.
Carisma Therapeutics reports Q3 2023 net loss of $21.4M; cash $94.1M funds into Q1 2025
Net loss of $21.4M for Q3 2023 vs. $18.3M for Q3 2022.
Carisma Therapeutics Reports Phase 1 CT-0508 Data Showing Safety and Biomarker Correlation
CT-0508 is a HER2-targeted CAR-M therapy for HER2 overexpressing cancers; 14 patients treated across group 1 (n=9) and group 2 (n=5).
Carisma Q2 net loss $19.9M, cash $117.1M; dosed first patient in CT-0508+KEYTRUDA combo trial
Dosed first patient in Phase 1 trial of CT-0508 in combination with KEYTRUDA for HER2-overexpressing solid tumors.
Authorized common stock increased from 100M to 350M shares (vote: 29.4M for, 1.6M against).
Carisma Therapeutics Q1 net loss widens to $24.6M; cash post-merger $139M
Net loss of $24.6M in Q1 2023, vs $11.3M in Q1 2022, driven by higher R&D and G&A expenses.
Carisma FY2022 net loss $61.2M, rev $9.8M; merger closed
Net loss of $61.2M for year ended Dec 31, 2022 (basic EPS $54.65 loss); compared to $40.8M net loss in 2021.
Carisma Therapeutics completes reverse merger with Sesen Bio; begins trading as CARM
Merger closed March 7, 2023; Sesen Bio renamed Carisma Therapeutics; ticker changes from SESN to CARM on Nasdaq.
Sesen Bio to pay $0.36/share special dividend and issue CVR upon merger close on March 7
Special cash dividend of $75M (~$0.36/share) payable by March 10 to holders of record March 7, contingent on merger closing.
Sesen Bio stockholders approve merger with Carisma; declares $75M special dividend
Over 88% of votes cast approved the merger with Carisma Therapeutics; merger expected to close March 7, 2023.
Sesen Bio reports Q4 net loss $7.6M; reiterates support for Carisma merger ahead of shareholder vote
Q4 net loss $7.6M ($0.04/shr) vs net income $8.9M in Q4 2021; FY net loss $19.9M ($0.10/shr).
Nasdaq Panel granted exception from $1.00 bid price rule to complete merger with Carisma by March 10, 2023.
Sesen Bio raises special dividend to $75M, extends CVR through 2027; activist investors back merger
Special cash dividend increased to $75M ($0.36/share) from prior ~$70M; up from original $25M.
Sesen Bio merger partner Carisma appoints Moderna CSO Lin Guey to SAB; merger on track for Q1 2023
Carisma Therapeutics appointed Lin Guey, PhD (Chief Scientific Officer of Moderna's External Research Ventures) to its Scientific Advisory Board.
Sesen Bio discloses ~$0.34/shr special dividend, 25.2% stake in combined company in Carisma merger
Expected one-time cash dividend of ~$70M ($0.34/shr) upon merger close; plus CVR up to $0.14/shr from legacy asset sales and Roche milestone.
Class action securities litigation settlement receives final court approval
U.S. District Court for Southern District of New York granted final approval on January 31, 2023.
Carisma appoints prominent oncologist to SAB; merger on track for Q1 2023
Padmanee Sharma, MD, PhD, from MD Anderson, appointed to Carisma's Scientific Advisory Board.
Sesen Bio receives Nasdaq delisting notice; warns of dissolution if merger fails
Nasdaq notified Sesen on Jan 25, 2023 of non-compliance with $1.00 bid price; delisting unless hearing requested.
Sesen Bio Amends Merger with Carisma: Special Dividend Raised to ~$70M, CVR Expanded
Expected special cash dividend increased from up to $25M to ~$70M ($0.34/share); up from ~$0.12.
Sesen Bio terminates license agreement with Qilu Pharma; pays $1.4M termination fee
Terminated exclusive license agreement with Qilu Pharmaceutical for Vicineum in Greater China.
Sesen Bio reports Q3 net income $20.5M, announces merger with Carisma Therapeutics
Merger with Carisma: Sesen stockholders own ~41.7%, Carisma ~58.3% of combined company with ~$180M cash.
On October 30, 2024, the Board elected Sohanya Cheng as a director of the Company, effective October 31, 2024.
On October 24, 2024, Michael Torok notified Carisma Therapeutics Inc. (the “Company”) of his decision to resign from the Company’s board of directors (the “Board”), effective October 31, 2024.
On June 26, 2024, each of Regina Hodits, Ph.D. and Björn Odlander, M.D., Ph.D. notified Carisma Therapeutics Inc. (the “Company”) of their respective decisions to resign from the Company’s board of directors, effective June 30, 2024.
On June 26, 2024, each of Regina Hodits, Ph.D. and Björn Odlander, M.D., Ph.D. notified Carisma Therapeutics Inc. (the “Company”) of their respective decisions to resign from the Company’s board of directors, effective June 30, 2024.
On June 26, 2024, the board of directors elected Marella Thorell and David Scadden, M.D. as directors of the Company, effective June 30, 2024.
On June 26, 2024, the board of directors elected Marella Thorell and David Scadden, M.D. as directors of the Company, effective June 30, 2024.
the Board was increased to seven members and the Board and its committees were reconstituted, consisting of six directors designated by Carisma, who are Steven Kelly, Regina Hodits, Ph.D., Briggs Morrison, M.D., Björn Odlander, M.D., Ph.D., Chidozie Ugwumba and Sanford Zweifach, and one director designated by the Company, who is Michael Torok.
Thomas R. Cannell, Jay S. Duker, M.D., Peter K Honig, M.D., Michael A.S. Jewett, M.D., Jason A. Keyes and Carrie L. Bourdow resigned from the Board and committees of the Board on which they respectively served, which resignations were not the result of any disagreements with the Company relating to the Company’s operations, policies or practices.
Thomas R. Cannell, Jay S. Duker, M.D., Peter K Honig, M.D., Michael A.S. Jewett, M.D., Jason A. Keyes and Carrie L. Bourdow resigned from the Board and committees of the Board on which they respectively served, which resignations were not the result of any disagreements with the Company relating to the Company’s operations, policies or practices.
the Board was increased to seven members and the Board and its committees were reconstituted, consisting of six directors designated by Carisma, who are Steven Kelly, Regina Hodits, Ph.D., Briggs Morrison, M.D., Björn Odlander, M.D., Ph.D., Chidozie Ugwumba and Sanford Zweifach, and one director designated by the Company, who is Michael Torok.
Thomas R. Cannell, Jay S. Duker, M.D., Peter K Honig, M.D., Michael A.S. Jewett, M.D., Jason A. Keyes and Carrie L. Bourdow resigned from the Board and committees of the Board on which they respectively served, which resignations were not the result of any disagreements with the Company relating to the Company’s operations, policies or practices.
Thomas R. Cannell, Jay S. Duker, M.D., Peter K Honig, M.D., Michael A.S. Jewett, M.D., Jason A. Keyes and Carrie L. Bourdow resigned from the Board and committees of the Board on which they respectively served, which resignations were not the result of any disagreements with the Company relating to the Company’s operations, policies or practices.
Max materiality 1.00 · Median 0.70 · Most common event other_material