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Cue Biopharma raises $50M in private placement led by Cormorant and Columbia Threadneedle
Gross proceeds of $50M from sale of 1,418,071 shares at $33.21/share and pre-funded warrants for 87,500 shares at $33.209.
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Cue Biopharma stockholders approve 2026 stock plan and warrant issuance
Warrant share issuance from May 2026 licensing transaction approved (1.78M For, 113K Against).
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Cue Biopharma appoints new directors, chief legal officer, and accounting officer; board size reduced
Resignations of directors Jill Broadfoot, Peter Kiener, Frank Morich, and Patrick Verheyen effective May 29, 2026.
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Cue Biopharma Q1 net loss $5.2M; appoints new CEO, $30M private placement, CUE-221 license
Net loss $5.2M ($1.08 EPS) vs $12.3M loss in Q1 2025; revenue $5.7M from Boehringer collaboration.
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Cue Biopharma licenses ex-China rights to anti-IgE mAb Ascendant-221; raises $30M; appoints new CEO
License with Ascendant Health Sciences: $15M upfront, up to $676.5M milestones, tiered high-single-to-low-double-digit royalties on ex-China sales.
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Cue Biopharma files 1-for-30 reverse stock split to maintain Nasdaq listing
1-for-30 reverse stock split effective 5:00 PM ET on April 23, 2026; no fractional shares, cash in lieu.
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Cue Biopharma stockholders approve reverse stock split with ratio 1:30 to 1:50
Elected Pasha Sarraf, Peter A. Kiener, Frank Morich, Pamela Garzone, Patrick Verheyen, and Jill Broadfoot to the Board.
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Cue Biopharma achieves preclinical milestone with Boehringer Ingelheim; $7.5M payment due May 2026
Boehringer Ingelheim approved selection of first compound for lead optimization under April 2025 collaboration.
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Cue Biopharma CEO Usman Azam resigns; Lucinda Warren named Interim CEO
Usman Azam resigned as President, CEO and Board member effective March 26, 2026.
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Cue Biopharma reports Q4 net income of $1.6M on $21.9M collab revenue from ImmunoScape; cash $27.1M
Net income $1.585M ($0.01 EPS) in Q4 2025 vs net loss $9.496M in Q4 2024; full-year net loss $26.6M vs $40.7M.
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Cue Biopharma sets 2026 annual meeting for April 13; shareholder deadlines on Feb 28.
Annual meeting date: April 13, 2026.
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Cue Biopharma appoints CBO Lucinda Warren as CFO effective Feb 9, 2026
Lucinda Warren, previously CBO, named Chief Financial & Business Officer; assumes principal financial/accounting officer duties.
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Cue Biopharma raises ~$10M in dilutive public offering; cash runway through Q1 2027
Gross proceeds ~$10M from 35.7M shares/pre-funded warrants and 17.9M warrants at $0.28 combined offering price.
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Cue Biopharma posts updated corporate presentation on website; no specific new facts disclosed
Company made an updated corporate presentation available on its website on November 24, 2025.
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Cue Biopharma CMO Matteo Levisetti to depart Nov 28; gets $556,838 severance
Chief Medical Officer Matteo Levisetti will terminate employment effective November 28, 2025.
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Cue Biopharma Q3 net loss $0.07/sh; ImmunoScape deal $15M upfront; new CEO
Q3 net loss $7.45M ($0.07 EPS); revenue $2.15M (down 36% YoY); cash $11.7M (down 48% from Dec 2024).
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Cue Biopharma licenses CUE-100 series to ImmunoScape; receives $15M cash and 40% equity
Collaboration with ImmunoScape to develop 'Seed-and-Boost' TCR-T cell therapy for solid tumors using CUE-100 series.
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Cue Biopharma appoints Usman Azam as CEO, succeeding Daniel Passeri who transitions to advisor
Usman Azam appointed President and CEO effective Sept 29, 2025; succeeds Daniel Passeri who retires and becomes strategic advisor.
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Cue Biopharma Q2 net loss $8.5M; BI deal with $12M upfront, $345M milestones
Net loss $8.5M ($0.09/share) vs $10.2M in Q2 2024; collaboration revenue $3.0M.
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Cue Biopharma reduces monthly rent 37% and extends Boston lease to April 2028
Monthly rent cut from $235,884 to $147,546, effective June 30, 2025.
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Cue Biopharma CFO resigns, elects Jill Broadfoot to board, increases authorized shares to 310M
CFO Kerri-Ann Millar resigns effective June 13, 2025; CEO Daniel Passeri will be interim principal financial and accounting officer.
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Cue Biopharma Q1 net loss $12.3M; announces BI collaboration for CUE-501 and $20M capital raise
Net loss $12.3M ($0.17 EPS) vs $12.3M ($0.25) YoY; revenue $0.4M down from $1.7M.
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Cue Biopharma prices $20M public offering; $13.1M cash; runway into Q2 2026
Pricing of 13.53M common shares + warrants at $0.79/unit; $20M gross proceeds.
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Cue Biopharma inks collaboration with Boehringer Ingelheim for B cell depletion; $12M upfront
Upfront payment of $12M; eligible for up to $345M in success-based research, development, and commercial milestones.
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Cue Biopharma Q4 2024 net loss narrows to $9.5M; cash at $22.5M; pipeline pivots to autoimmune
Net loss of $9.5M in Q4 2024 ($0.13/share) vs $13.4M in Q4 2023; full year net loss $40.7M.
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Cue Biopharma appoints Pasha Sarraf to board of directors
Pasha Sarraf appointed to board on March 10, 2025.
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Cue Biopharma Q3 net loss narrows to $8.7M; CUE-101 combo shows 46% ORR in HPV+ HNSCC
Net loss of $8.7M ($0.17 per share) vs $11.0M loss ($0.24) in Q3 2023; collaboration revenue rose to $3.3M.
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Cue Biopharma stockholders approve doubling authorized common stock to 200M shares
Authorized shares increased from 110M to 210M total, common from 100M to 200M.
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Cue Biopharma amends SVB credit agreement, eliminates $20M cash reserve requirement
Second Amendment dated Oct 2, 2024 removes $20M minimum cash requirement from SVB loan agreement.
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Cue Biopharma prices $12M public offering of stock and warrants, extends cash runway into Q4 2025
10.6M shares of common stock and 2.9M common stock warrants offered at $0.50 per unit; pre-funded warrants for 12.4M shares at $0.499.
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Director Michael J. Fox resigns from Cue Biopharma board effective Aug 28, 2024
Michael J. Fox resigned as director and from all board committees on August 28, 2024.
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Cue Biopharma receives Nasdaq deficiency notice for bid price below $1.00
Received Nasdaq notice on August 15, 2024 for failure to meet minimum bid price of $1.00 for 30 consecutive business days.
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Cue Biopharma restructures, cuts workforce 25%, extends cash runway to mid-2025
Reduces workforce by ~25% across R&D and G&A; CEO Daniel Passeri takes 50% salary reduction, execs forgo 2023 bonuses.
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Cue Biopharma appoints Michael J. Fox to board; grants 48,800-share option
Michael J. Fox appointed to Board and Compensation Committee effective June 5, 2024.
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Cue Biopharma reports Q1 2024 net loss $12.3M, cash $41M into Q1 2025
Collaboration revenue $1.7M vs $0.2M YoY; net loss $0.25/share vs $0.29.
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Cue Biopharma director Aaron Fletcher resigns from board effective Oct 9, 2023
Aaron Fletcher notified Cue Biopharma of resignation from Board and all committees.
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Cue Biopharma announces results of 2023 Annual Meeting; all director nominees elected
All 7 director nominees elected; Daniel Passeri received 11,665,042 for, 2,353,834 withheld.
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Cue Biopharma appoints Pamela Garzone to board of directors
Pamela Garzone appointed to board effective April 19, 2023, following recommendation of committee.
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Cue Biopharma appoints Patrick Verheyen to Board of Directors
Patrick Verheyen appointed to the Board on April 11, 2023.
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Director Howson to retire from Cue Biopharma board at 2023 annual meeting
Ms. Howson informed the board on March 7, 2023 of her retirement.
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Cue Biopharma raises $30M in PIPE financing; sells shares, pre-funded warrants, and warrants
Gross proceeds of $30M; net proceeds ~$28.2M after fees.
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Cue Biopharma Director Cameron Gray Resigns from Board
Cameron Gray notified Cue Biopharma of his resignation as a Board member on June 16, 2022.
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Cue Biopharma reports 2022 annual meeting voting results
All seven director nominees elected (Driscoll, Fletcher, Gray, Howson, Kiener, Morich, Passeri).
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Cue Biopharma signs 4-year license for Boston office/lab space; monthly rent $200,700
Lease covers ~13,000 sq ft at 40 Guest Street, Boston; term April 15, 2022 to April 14, 2026.
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Cue Biopharma enters $20M SVB loan facility with tranche A of $10M available immediately
Tranche A of $10M funded at closing; two additional tranches up to $5M each contingent on CUE-101 data and equity proceeds.
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Cue Biopharma presents at Stifel Healthcare Conference; corporate slides attached
Presentation on Nov 15, 2021 at Stifel Healthcare Conference.
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Cue Biopharma enters $80M at-the-market equity offering agreement with Jefferies
Company enters Open Market Sale Agreement with Jefferies LLC to sell up to $80M of common stock at-the-market.