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Cue Biopharma raises $50M in private placement led by Cormorant and Columbia Threadneedle
Gross proceeds of $50M from sale of 1,418,071 shares at $33.21/share and pre-funded warrants for 87,500 shares at $33.209.
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Cue Biopharma appoints new directors, chief legal officer, and accounting officer; board size reduced
Resignations of directors Jill Broadfoot, Peter Kiener, Frank Morich, and Patrick Verheyen effective May 29, 2026.
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Cue Biopharma Q1 net loss $5.2M; appoints new CEO, $30M private placement, CUE-221 license
Net loss $5.2M ($1.08 EPS) vs $12.3M loss in Q1 2025; revenue $5.7M from Boehringer collaboration.
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Cue Biopharma licenses ex-China rights to anti-IgE mAb Ascendant-221; raises $30M; appoints new CEO
License with Ascendant Health Sciences: $15M upfront, up to $676.5M milestones, tiered high-single-to-low-double-digit royalties on ex-China sales.
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Cue Biopharma files 1-for-30 reverse stock split to maintain Nasdaq listing
1-for-30 reverse stock split effective 5:00 PM ET on April 23, 2026; no fractional shares, cash in lieu.
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Cue Biopharma achieves preclinical milestone with Boehringer Ingelheim; $7.5M payment due May 2026
Boehringer Ingelheim approved selection of first compound for lead optimization under April 2025 collaboration.
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Cue Biopharma CEO Usman Azam resigns; Lucinda Warren named Interim CEO
Usman Azam resigned as President, CEO and Board member effective March 26, 2026.
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Cue Biopharma reports Q4 net income of $1.6M on $21.9M collab revenue from ImmunoScape; cash $27.1M
Net income $1.585M ($0.01 EPS) in Q4 2025 vs net loss $9.496M in Q4 2024; full-year net loss $26.6M vs $40.7M.
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Cue Biopharma raises ~$10M in dilutive public offering; cash runway through Q1 2027
Gross proceeds ~$10M from 35.7M shares/pre-funded warrants and 17.9M warrants at $0.28 combined offering price.
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Cue Biopharma CMO Matteo Levisetti to depart Nov 28; gets $556,838 severance
Chief Medical Officer Matteo Levisetti will terminate employment effective November 28, 2025.
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Cue Biopharma licenses CUE-100 series to ImmunoScape; receives $15M cash and 40% equity
Collaboration with ImmunoScape to develop 'Seed-and-Boost' TCR-T cell therapy for solid tumors using CUE-100 series.
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Cue Biopharma appoints Usman Azam as CEO, succeeding Daniel Passeri who transitions to advisor
Usman Azam appointed President and CEO effective Sept 29, 2025; succeeds Daniel Passeri who retires and becomes strategic advisor.
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Cue Biopharma Q2 net loss $8.5M; BI deal with $12M upfront, $345M milestones
Net loss $8.5M ($0.09/share) vs $10.2M in Q2 2024; collaboration revenue $3.0M.
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Cue Biopharma CFO resigns, elects Jill Broadfoot to board, increases authorized shares to 310M
CFO Kerri-Ann Millar resigns effective June 13, 2025; CEO Daniel Passeri will be interim principal financial and accounting officer.
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Cue Biopharma Q1 net loss $12.3M; announces BI collaboration for CUE-501 and $20M capital raise
Net loss $12.3M ($0.17 EPS) vs $12.3M ($0.25) YoY; revenue $0.4M down from $1.7M.
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Cue Biopharma prices $20M public offering; $13.1M cash; runway into Q2 2026
Pricing of 13.53M common shares + warrants at $0.79/unit; $20M gross proceeds.
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Cue Biopharma inks collaboration with Boehringer Ingelheim for B cell depletion; $12M upfront
Upfront payment of $12M; eligible for up to $345M in success-based research, development, and commercial milestones.
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Cue Biopharma Q4 2024 net loss narrows to $9.5M; cash at $22.5M; pipeline pivots to autoimmune
Net loss of $9.5M in Q4 2024 ($0.13/share) vs $13.4M in Q4 2023; full year net loss $40.7M.
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Cue Biopharma Q3 net loss narrows to $8.7M; CUE-101 combo shows 46% ORR in HPV+ HNSCC
Net loss of $8.7M ($0.17 per share) vs $11.0M loss ($0.24) in Q3 2023; collaboration revenue rose to $3.3M.
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Cue Biopharma prices $12M public offering of stock and warrants, extends cash runway into Q4 2025
10.6M shares of common stock and 2.9M common stock warrants offered at $0.50 per unit; pre-funded warrants for 12.4M shares at $0.499.
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Cue Biopharma receives Nasdaq deficiency notice for bid price below $1.00
Received Nasdaq notice on August 15, 2024 for failure to meet minimum bid price of $1.00 for 30 consecutive business days.
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Cue Biopharma restructures, cuts workforce 25%, extends cash runway to mid-2025
Reduces workforce by ~25% across R&D and G&A; CEO Daniel Passeri takes 50% salary reduction, execs forgo 2023 bonuses.
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Cue Biopharma reports Q1 2024 net loss $12.3M, cash $41M into Q1 2025
Collaboration revenue $1.7M vs $0.2M YoY; net loss $0.25/share vs $0.29.
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Cue Biopharma raises $30M in PIPE financing; sells shares, pre-funded warrants, and warrants
Gross proceeds of $30M; net proceeds ~$28.2M after fees.
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Cue Biopharma Director Cameron Gray Resigns from Board
Cameron Gray notified Cue Biopharma of his resignation as a Board member on June 16, 2022.
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Cue Biopharma signs 4-year license for Boston office/lab space; monthly rent $200,700
Lease covers ~13,000 sq ft at 40 Guest Street, Boston; term April 15, 2022 to April 14, 2026.
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Cue Biopharma enters $20M SVB loan facility with tranche A of $10M available immediately
Tranche A of $10M funded at closing; two additional tranches up to $5M each contingent on CUE-101 data and equity proceeds.
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Cue Biopharma enters $80M at-the-market equity offering agreement with Jefferies
Company enters Open Market Sale Agreement with Jefferies LLC to sell up to $80M of common stock at-the-market.