Eliot M. Lurier
Mr. Hoffman succeeds Eliot M. Lurier, who passed away in December 2023
Highest-materiality recent filing
Phase 3 LEVEL trial results to be presented in Late-Breaking Clinical Science session at ESC Congress 2026 (Aug 28-31, Munich).
Tenax Therapeutics enters supply agreement with Orion; extends regulatory approval deadline to 2035
Supply Agreement with Orion for oral levosimendan; 5-year initial term, auto-renewing 3-year periods.
Tenax adopts CIC/Severance Plans; amends CEO Giordano's agreement
Board adopted double-trigger Change in Control Plan and Severance Plan on June 26, 2026.
Tenax Therapeutics reports results of 2026 annual shareholder meeting
Stockholders elected seven directors: June Almenoff (17.36M for), Michael Davidson (15.76M), Declan Doogan, Christopher T. Giordano, Robyn M. Hunter, Gerald T. Proehl, Stuart Rich.
Tenax Q1 net loss $15.7M; cash $118.8M; Phase 3 topline data expected Q3 2026
Net loss of $15.7M for Q1 2026 vs $10.4M in Q1 2025; R&D expense rose to $11.5M from $5.7M.
Tenax Therapeutics appoints Thomas R. Staab, II as CFO effective May 11, 2026
Staab, a 25-year healthcare finance veteran, most recently CFO of LENSAR (LNSR) until May 2026.
Tenax Therapeutics reports Q4/FY2025 loss; LEVEL study fully enrolled, topline Q3 2026
Achieved 230-patient randomization target in Phase 3 LEVEL study; topline data expected Q3 2026.
Tenax CMO Dr. Stuart Rich moves to 4-day work week; salary prorated 80%
Effective Jan 1, 2026, Dr. Rich will average 4 days per week as CMO.
Tenax Therapeutics confirms LEVEL Phase 3 trial enrollment on track; initiates global LEVEL-2 study
Blinded Sample Size Re-estimation (BSSR) shows LEVEL is powered >90% to detect 25m change in 6MWD primary endpoint.
Tenax Therapeutics Q3 net loss $15.8M; Phase 3 LEVEL enrollment on track
Net loss of $15.8M for Q3 2025 vs $4.0M in Q3 2024; R&D expenses $10.3M (up from $3.1M).
Tenax Therapeutics receives EPO intention to grant patent for levosimendan in PH-HFpEF through 2040
EPO intends to grant patent covering TNX-103 (oral levosimendan) and other formulations for PH-HFpEF.
Amendment with Orion grants Tenax exclusive worldwide rights to develop, commercialize, and manufacture oral levosimendan products.
Net loss of $10.9M in Q2 2025 vs $3.6M in Q2 2024; R&D spend $6.1M, G&A $5.7M.
Tenax Therapeutics shareholders approve officer exculpation, reject meeting-vote mandate
Shareholders approved officer exculpation amendment (2,458,203 for, 10,244 against); effective upon filing.
Tenax Therapeutics Q1 net loss $10.4M; Phase 3 LEVEL enrollment on track for year-end 2025
Net loss $10.4M in Q1 2025 vs $3.8M in Q1 2024; company is a development-stage biotech with no revenue.
Net loss for FY2024 was $17.6M vs $7.7M in 2023; Q4 net loss $6.3M vs $3.2M.
Tenax raises $25M, expands Phase 3 LEVEL study to 230 patients, adds LEVEL-2 trial
Private placement with RTW Investments grossed ~$25M; issued 378K shares + pre-funded warrants for 3.76M shares at $6.04/$6.03.
Tenax Therapeutics appoints Thomas A. McGauley as Interim CFO, effective Dec 2, 2024
Thomas A. McGauley appointed Interim CFO and principal financial/accounting officer, replacing Lawrence R. Hoffman.
Tenax Therapeutics Q3 net loss $4.0M; raised $100M private placement
Net loss of $4.0M for Q3 2024 vs $2.0M in Q3 2023; R&D expenses $3.1M (up from $1.1M).
Stockholders approve 7.9M share increase in 2022 Stock Incentive Plan
Approved Amendment No. 2 to 2022 Stock Incentive Plan, increasing authorized shares to 8,336,600 (7,935,912 new shares).
Tenax Therapeutics reports Q2 net loss of $3.6M, cash $9.4M; raised $100M
Net loss of $3.6M ($1.83/sh) vs loss of $1.1M ($4.00/sh) in Q2 2023.
Tenax Therapeutics closes $100M private placement to fund Phase 3 levosimendan program
Gross proceeds of ~$100M from oversubscribed private placement led by BVF Partners.
Tenax Therapeutics Raises $100M in Oversubscribed Private Placement Led by BVF Partners
Gross proceeds ~$100M from 1.45M shares, 31.9M pre-funded warrants, and 16.7M warrants at $3.00/share (warrant strike $4.50).
Tenax Therapeutics expands equity pool by 400k shares; CMO shifts to part-time
Stockholders approved Amendment No. 1 to 2022 Stock Incentive Plan, increasing authorized shares to 400,688.
Tenax Therapeutics Q1 net loss widens to $3.8M; Phase 3 LEVEL study enrolling
Net loss of $3.8M vs $1.4M in Q1 2023; R&D expenses rose to $2.7M from $0.3M.
Tenax Therapeutics reports FY2023 net loss $7.7M; Phase 3 LEVEL trial underway
Cash $9.8M at Dec 31, 2023; Feb 2024 public offering netted ~$8.0M.
Tenax Therapeutics regains Nasdaq minimum float compliance; deficiency closed
Received Nasdaq notice on Feb 22, 2024 confirming over 500,000 publicly held shares.
Tenax Therapeutics expands levosimendan license to worldwide rights from Orion
Amendment expands Tenax's exclusive global rights to levosimendan for PH-HFpEF from North America to worldwide.
Tenax Therapeutics prices $9M public offering of common stock and warrants
1.6M shares or pre-funded warrants plus 3.2M common warrants at $5.65/unit.
First patient enrolled in Phase 3 LEVEL study of oral TNX-103 (levosimendan) for PH-HFpEF; 152-patient trial.
USPTO allows patent covering levosimendan use in PH-HFpEF through 2040
USPTO Notice of Allowance for patent covering oral (TNX-103), IV, subcutaneous levosimendan, active metabolites, and drug combos for PH-HFpEF.
Tenax Therapeutics regains compliance with Nasdaq minimum bid price rule
Received Nasdaq written confirmation on Jan 18, 2024, after 10 consecutive trading days (Jan 3-17) closing at $1.00 or greater.
Tenax Therapeutics receives Nasdaq delisting notice; appoints interim CFO Lawrence Hoffman
Nasdaq notified Tenax on Jan 11, 2024 that it fails minimum 500,000 publicly held shares after 1-for-80 reverse split.
Tenax Therapeutics announces 1-for-80 reverse stock split effective Jan 2, 2024
Reverse split at 1:80 ratio effective 5:00 pm ET on Jan 2, 2024; trading on Nasdaq split-adjusted Jan 3 under TENX.
Tenax Therapeutics shareholders approve reverse stock split authorization
Reverse split ratio range 1:10 to 1:80, exact ratio set by board; authorized until Nov 30, 2024.
FDA cleared IND for TNX-103 (oral levosimendan) to treat PH-HFpEF, enabling Phase 3 LEVEL study in Q4 2023.
Tenax Therapeutics gets Nasdaq extension to March 25, 2024 for $1 bid price rule
Nasdaq granted extension through March 25, 2024 to regain compliance with $1.00 minimum bid price (Rule 5550(a)(2)).
Tenax Therapeutics amends bylaws to lower quorum to one-third, allow director removal without cause
Quorum for stockholder meetings reduced to one-third of shares entitled to vote from previous higher threshold.
Tenax Therapeutics receives U.S. patent for oral levosimendan (TNX-103) in PH-HFpEF, expiring 2040
USPTO granted Patent No. 11,701,355 for oral levosimendan (TNX-103) to treat PH-HFpEF, with exclusivity through December 2040.
Tenax shareholders reject reverse stock split and stock plan amendment; directors elected
All seven director nominees elected: June Almenoff, Michael Davidson, Declan Doogan, Christopher Giordano, Robyn Hunter, Gerald Proehl, Stuart Rich.
Tenax Therapeutics receives USPTO Notice of Allowance for oral levosimendan patent in PH-HFpEF
Patent covers oral levosimendan (TNX-103) for PH-HFpEF; term through Dec 2040, possible extension beyond.
Tenax prioritizes oral levosimendan Phase 3 for PH-HFpEF in 2023
Company to initiate Phase 3 trial of TNX-103 (oral levosimendan) for PH-HFpEF in 2023.
Tenax Therapeutics receives Nasdaq bid price deficiency notice; 180 days to regain compliance
Nasdaq notified Tenax on March 29, 2023 that bid price closed below $1.00 for 30 consecutive business days.
Tenax Therapeutics receives US patent for IV levosimendan in PH-HFpEF, expiring Dec 2040
U.S. Patent No. 11,607,412 covers IV levosimendan for pulmonary hypertension with HFpEF.
Tenax Therapeutics terminates HQ lease with $169,867 payment; no further obligations
Lease termination with CCP Concourse, LLC, effective Feb 8, 2023.
Tenax Therapeutics raises ~$15.6M in public offering of common stock and warrants
Priced 8,666,666 shares (or pre-funded warrants) plus 17,333,332 warrants at $1.80/unit.
Tenax Therapeutics granted US patent covering IV levosimendan for PH-HFpEF until 2040
USPTO Notice of Allowance for patent covering IV levosimendan in PH-HFpEF; patent expected to last until 2040.
Tenax regains compliance with Nasdaq minimum bid price rule
Nasdaq confirmed compliance on Jan 20, 2023 after stock closed at $1.00+ for ten consecutive trading days.
Tenax Therapeutics effects 1-for-20 reverse stock split to meet Nasdaq minimum bid price
Reverse stock split at 1-for-20 ratio effective 5:00 p.m. ET on January 4, 2023.
Tenax Therapeutics announces positive oral levosimendan data in PH-HFpEF patients at HFSA meeting
18 PH-HFpEF patients transitioned from IV to oral levosimendan with no serious adverse events reported.
Mr. Hoffman succeeds Eliot M. Lurier, who passed away in December 2023
On January 9, 2024, the Company’s Board of Directors (the “Board”) appointed Lawrence R. Hoffman as Interim Chief Financial Officer of the Company effective January 11, 2024
On June 10, 2022, Steven Boyd and Keith Maher, MD, both of Armistice Capital, LLC, the investment manager to Armistice Capital Master Fund Ltd. (the “Master Fund”), notified the Board of Directors (the “Board”) of Tenax Therapeutics, Inc. (the “Company”) that they have resigned from the Board.
On June 10, 2022, Steven Boyd and Keith Maher, MD, both of Armistice Capital, LLC, the investment manager to Armistice Capital Master Fund Ltd. (the “Master Fund”), notified the Board of Directors (the “Board”) of Tenax Therapeutics, Inc. (the “Company”) that they have resigned from the Board.
On January 26, 2022, the Board of Directors (the “Board”) of Tenax Therapeutics, Inc. (the “Company”) appointed Robyn M. Hunter as a member of the Board, effective January 28, 2022, to serve until the Company’s 2022 annual meeting of stockholders or until her successor is duly elected and qualified.
Michael B. Jebsen, the Company's President and Chief Financial Officer, agreed that Mr. Jebsen would separate from the Company effective October 29, 2021
the Company’s current Chief Executive Officer and principal executive officer, Christopher T. Giordano, will assume the additional position of President of the Company.
Michael B. Jebsen, the Company's President and Chief Financial Officer, agreed that Mr. Jebsen would separate from the Company effective October 29, 2021
the Company has entered into a consulting agreement with Danforth Advisors, LLC (“Danforth”), dated October 14, 2021, providing for the engagement of Eliot M. Lurier, a consultant with Danforth, as Interim Chief Financial Officer of the Company
On September 8, 2021, James Mitchum notified the Company that he is voluntarily resigning from the Board and its Audit and Compliance Committee and Compensation Committee, effective immediately.
On July 13, 2021, Anthony A. DiTonno will retire as the Chief Executive Officer of the Company and as a member of the Company’s Board of Directors (the “Board”) effective as of July 13, 2021.
On July 6, 2021, the Board appointed Christopher T. Giordano as the Company’s Chief Executive Officer and a member of its Board of Directors, effective July 14, 2021.
Max materiality 0.85 · Median 0.65 · Most common event other_material